Clinical outcome in resistant HIV-2 infection treated with raltegravir and maraviroc.
Author(s): Armstrong-James D, Stebbing J, Scourfield A, Smit E, Ferns B, Pillay D, Nelson M
Affiliation(s): Imperial College, St. Stephens AIDS Trust, Chelsea and Westminster Hospital, London, UK.
Publication date & source: 2010-05, Antiviral Res., 86(2):224-6. Epub 2010 Mar 6.
Therapy for infection with HIV-2 remains limited. We report an HIV-2-infected patient in whom genotyping demonstrated PI, NRTI and NNRTI resistance, with a subsequent response to raltegravir- and maraviroc-based therapy. Further studies are required to assess the clinical efficacy of maraviroc in HIV-2 infection.
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