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[Comparative study of the use of sennoside A and B vs polyethylene glycol and electrolytes in anterograde preparation of the colon]

Author(s): Farca Belsaguy A, Fernandez Castro E, Presenda Miller F

Affiliation(s): Servicio de Gastroenterologia, Hospital Dr. Manuel Gea Gonzalez, Mexico, D.F.

Publication date & source: 1999-04, Rev Gastroenterol Mex., 64(2):85-8.

Publication type: Clinical Trial; Randomized Controlled Trial

OBJECTIVE: Compare effectiveness of antegrade bowel preparation by liquid diet, polyethylenglycol (PEG) and electrolytes solution plus sennosides A and B, vs. liquid diet plus sennosides A and B only. BACKGROUND DATA: Preparation for colonoscopy with a balanced solution (PEG and electrolytes) has some physiological advantages. Nonetheless, drawbacks of such preparation include nasty flavor, large volumes and low availability in our country. METHOD: A randomized, comparative, prospective, transversal and blind trial that included 200 patients scheduled for colonoscopy were randomly assigned (one hundred each group) to receive: group 1: liquid diet, sennosides A and B and a two litter of solution with PEG and electrolytes; and group 2: liquid diet plus sennosides A and B. Compliance, tolerance and effectiveness of both preparations were evaluated blindly. The results were assessed by Student's T test. RESULTS: The effectiveness of group 2 preparation proved superior (p < 0.05) to group 1. Tolerance and side effects were similar for both groups with no related complications.

Page last updated: 2006-01-31

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