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Efficacy of quinupristin/dalfopristin versus vancomycin, alone or in combination with rifampicin, against methicillin-resistant Staphylococcus aureus in a rabbit arthritis model.

Author(s): Hamel A, Caillon J, Jacqueline C, Batard E, Potel G

Affiliation(s): Universite de Nantes, Nantes Atlantique Universites, Therapeutiques cliniques et experimentales des infections, EA 3826, UFR Medecine, 1 rue G. Veil, F-44000 Nantes, France.

Publication date & source: 2008-02, Int J Antimicrob Agents., 31(2):158-60. Epub 2007 Nov 19.

We compared the efficacy of quinupristin/dalfopristin versus vancomycin, alone or in combination with rifampicin, in a rabbit model of methicillin-resistant Staphylococcus aureus-induced arthritis. Vancomycin, alone or in combination with rifampicin, and quinupristin/dalfopristin+rifampicin were significantly more effective than quinupristin/dalfopristin alone.

Page last updated: 2008-06-22

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