[Infections related to central venous catheters in children affected from malignant diseases].

Author(s): Handrup MM, Moller JK, Schroder H

Affiliation(s): Borneafdeling A4, Aarhus Universitetshospital, Skejby, 8200 Aarhus N, Denmark. Handrup@ki.au.dk

Publication date & source: 2011-06-27, Ugeskr Laeger., 173(26):1882-5.

Publication type: English Abstract

Central venous catheters (CVC) are an essential part of the treatment of children with haematological and oncological diseases. Unfortunately, CVC also represent a major risk factor of bloodstream infections. Catheter-related bloodstream infections (CRBSI) in children are often diagnosed based on blood cultures from the CVC only. Most CRBSI can be treated without catheter removal. On suspicion of CRBSI empirical antibiotic treatment with piperacillin-tazobactam, meropenem or ampicillin in combination with gentamicin is recommended. The systemic treatment can be combined with catheter-lock therapy.