Instant dentin hypersensitivity relief of a single topical application of an
in-office desensitizing paste containing 8% arginine and calcium carbonate: A
split-mouth, randomized-controlled study.
Author(s): Kapferer I, Pflug C, Kisielewsky I, Giesinger J, Beier US, Dumfahrt H.
Affiliation(s): Department of Restorative and Operative Dentistry, Dental School.
Publication date & source: 2012, Acta Odontol Scand. ,
Abstract Objective. The aim of this study was to evaluate the clinical efficacy
of an in-office desensitizing paste containing 8% arginine and calcium carbonate
relative to calcium carbonate alone in the reduction of dentin hypersensitivity
in a randomized, double-blind, split-mouth clinical trial. Materials and methods.
Sixty teeth (30 subjects) with an air blast hypersensitivity score of 2 or 3
(Schiff Cold Air Sensitivity Scale) were randomly assigned to one of two
treatment groups: (1) test paste containing 8% arginine and calcium carbonate
(elmex sensitive professional desensitizing paste) and (2) control paste: paris
white (calcium carbonate). Tactile and air blast dentin hypersensitivity
examinations were performed at baseline, immediately after paste application and
4 and 12 weeks later. Results. A statistically significant difference in air
blast (p = 0.001) and tactile (p = 0.047) hypersensitivity reduction over time
was observed between the two therapy modes. After 12-weeks, statistically
significant differences were indicated between the test and control group with
respect to baseline-adjusted mean tactile (41.94%; p = 0.038) and air blast
hypersensitivity scores (46.5%; p = 0.017). Conclusions. The tested in-office
desensitizing paste containing 8.0% arginine and calcium carbonate provides
significantly greater hypersensitivity relief compared to calcium carbonate
alone.
|