[Assessment of the antiphlogistic effect of naftifin-HCl in the UV-B erythema test]
Author(s): Kecskes A, Jahn P
Affiliation(s): Department Humanpharmakologie II, Schering AG Berlin.
Publication date & source: 1989-03, Hautarzt., 40(3):158-60.
Publication type: Clinical Trial; Controlled Clinical Trial
In a placebo-controlled double-blind comparative study conducted in 19 healthy volunteers, naftifin hydrochlorid cream was tested against clotrimazole 1%, clotrimazole 1%+hydrocortisone 1%, and various hydrocortisone preparations (0.5%; 1%; 2.5%) for erythema-suppressive effects. The anti-inflammatory effect of naftifine hydrochloride demonstrated earlier was confirmed in this study. The results prove a potency comparable to that of weak topical glucocorticosteroids.
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