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Safety and efficacy of low-dose esterified estrogens and methyltestosterone, alone or combined, for the treatment of hot flashes in menopausal women: a randomized, double-blind, placebo-controlled study.

Author(s): Liu J, Allgood A, Derogatis LR, Swanson S, O'Mahony M, Nedoss B, Soper H, Zbella E, Prokofieva SV, Zipfel L, Guo CY

Affiliation(s): Case Medical Center, MacDonald Women's Hospital, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.

Publication date & source: 2011-01, Fertil Steril., 95(1):366-8. Epub 2010 Sep 17.

Publication type: Randomized Controlled Trial

This study evaluated safety and efficacy of esterified estrogens and methyltestosterone administered alone or in combination for the treatment of hot flashes in menopausal women. The 0.30-mg esterified estrogens and 0.30-mg methyltestosterone combination was the lowest effective dose, and our results are consistent with the known safety profile of estrogen and androgen combination products. Copyright (c) 2011 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.

Page last updated: 2011-12-09

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