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Antibiotics for gram-positive bacterial infections: vancomycin, quinupristin-dalfopristin, linezolid, and daptomycin.

Author(s): Lundstrom TS, Sobel JD

Affiliation(s): Division of Infectious Diseases, Wayne State University-Detroit Medical Center, 4201 St. Antoine UHC 2B, Detroit, MI 48201, USA. tlundstrom@dmc.org

Publication date & source: 2004-09, Infect Dis Clin North Am., 18(3):651-68, x.

Publication type: Review

An overview of the mechanism of action, dosing, clinical indications, and toxicities of the glycopeptide vancomycin is provided. Emerging gram-positive bacterial resistance to antimicrobials and its mechanisms are reviewed. Strategies to control emergence of resistance are proposed. Newer antimicrobial agents with activity against vancomycin-resistant organisms are now available and play a critical role in the treatment of life-threatening infections.

Page last updated: 2006-01-31

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