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Antibiotics for gram-positive bacterial infections: vancomycin, teicoplanin, quinupristin/dalfopristin, oxazolidinones, daptomycin, dalbavancin, and telavancin.

Author(s): Nailor MD, Sobel JD

Affiliation(s): Department of Internal Medicine, Wayne State University, Detroit, MI 48201, USA.

Publication date & source: 2009-12, Infect Dis Clin North Am., 23(4):965-82, ix.

Publication type: Review

An overview of the mechanism of action, dosing, clinical indications, and toxicities of the glycopeptide vancomycin is provided. The emerging gram-positive bacterial resistance to antimicrobials and its mechanisms are reviewed. Strategies to control this emergence of resistance are expected to be proposed. Newer antimicrobial agents that have activity against vancomycin-resistant organisms are now available and play a critical role in the treatment of life-threatening infections.

Page last updated: 2010-10-05

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