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Tetracaine (ametop) compared to placebo for reducing pain associated with intramuscular injection of palivizumab (synagis).

Author(s): Newby BD, Faschoway GD, Soukoroff CI

Affiliation(s): Pharmacy Department, Surrey Memorial Hospital, Surrey, BC, Canada. brandi.newby@fraserhealth.ca

Publication date & source: 2009-12, J Pediatr Nurs., 24(6):529-33. Epub 2009 Jul 9.

Publication type: Randomized Controlled Trial

Infants receive many painful immunizations before they are 2 years old. The purpose of this study was to evaluate if topical tetracaine reduces the pain of intramuscular palivizumab compared to placebo. There were two study injections, one with tetracaine and one with placebo. Pain was scored by their parents and a pediatric nurse. Topical tetracaine was not associated with a significant reduction in pain score, although it did lead to faster recovery times. Additional pain-reduction strategies are required.

Page last updated: 2010-10-05

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