Polymyxin B and colistimethate are comparable as to efficacy and renal toxicity.
Author(s): Oliveira MS, Prado GV, Costa SF, Grinbaum RS, Levin AS
Affiliation(s): Department of Infection Control of Hospital das Clinicas, Rua Dr. Ovidio Pires de Campos, Sao Paulo-SP 05403-010, Brazil.
Publication date & source: 2009-12, Diagn Microbiol Infect Dis., 65(4):431-4. Epub 2009 Sep 3.
We compared 41 patients who received colistimethate with 41 who received polymyxin B for the treatment of serious infections caused by carbapenem-resistant Acinetobacter spp. and found both polymyxins have similar efficacy and toxicity.
|