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The impact of anti-inflammatory therapy on intraocular pressure reduction following selective laser trabeculoplasty.

Author(s): Realini T, Charlton J, Hettlinger M

Affiliation(s): West Virginia University Eye Institute, Morgantown, Huntington, West Virginia, USA.

Publication date & source: 2010-01, Ophthalmic Surg Lasers Imaging., 41(1):100-3.

Publication type: Comparative Study; Randomized Controlled Trial

BACKGROUND AND OBJECTIVE: To determine whether the use of postoperative topical anti-inflammatory therapy affects the intraocular pressure (IOP)-lowering efficacy of selective laser trabeculoplasty in eyes with primary open-angle glaucoma. PATIENTS AND METHODS: In this prospective, randomized, observer-masked study, 25 participants with primary open-angle glaucoma following bilateral 360 degrees selective laser trabeculoplasty used prednisolone acetate 1% four times daily in one randomly selected eye for 1 week. IOP was assessed at baseline and 1 week, 1 month, and 3 months after selective laser trabeculoplasty. RESULTS: Baseline IOP and selective laser trabeculoplasty treatment parameters were comparable in both groups. Mean IOP was similar in eyes that did and did not receive steroid therapy at 1 week (17.0 vs 16.3 mm Hg, respectively, P = .613), 1 month (16.8 vs 16.2 mm Hg, respectively; P = .571), and 3 months (16.0 vs 15.8 mm Hg, respectively; P = .819). CONCLUSION: A 1-week course of topical prednisolone acetate 1% four times daily did not affect the IOP-lowering effect of selective laser trabeculoplasty in eyes with primary open-angle glaucoma. Copyright 2010, SLACK Incorporated.

Page last updated: 2010-10-05

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