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Linezolid and quinupristin/dalfopristin: novel antibiotics for gram-positive infections of the skin.

Author(s): Schweiger ES, Scheinfeld NS, Tischler HR, Weinberg JM

Affiliation(s): Department of Dermatology, St. Luke's-Roosevelt Hospital Center, Beth Israel Medical Center, New York, New York, USA. jwein@bway.net

Publication date & source: 2003-08, J Drugs Dermatol., 2(4):378-83.

Publication type: Review

With the continuing development of clinical drug resistance among bacteria, the need for new, effective agents to treat multi-drug-resistant Gram-positive infections remains important. With treatment options limited, it has become critical to identify antibiotics with novel mechanisms of activity. Several new drugs have emerged as possible therapeutic alternatives. This review focuses on agents newly introduced and FDA-approved for the treatment of skin and skin structure infections: linezolid and quinupristin/dalfopristin.

Page last updated: 2006-01-31

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