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Promethazine toxicity in a seven-month-old Doberman pinscher.

Author(s): Staley EC, Staley EE

Affiliation(s): Veterinary Medical Clinic, Alamogordo, NM 88310, USA.

Publication date & source: 1995-06, Vet Hum Toxicol., 37(3):243-4.

Publication type: Case Reports

A 7-mo-old female Doberman Pinscher undergoing antibiotic treatment for tonsillitis was presented in near collapse with markedly low blood pressure, tachycardia, dilatation of pupils (non-responsive to light), and gastrointestinal distress. Since the owner could provide no history of significant toxin exposure, general supportive and non-specific toxicologic treatment protocols were initiated. Within 4 h marked improvement was observed. The owner's wife revealed that promethazine suppositories had been administered at a toxic level to control the vomition accompanying the tonsillitis.

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