Selenium, thiobarbituric acid reactive substances, and thyroid hormone activation in broilers supplemented with selenium as selenized yeast or sodium selenite.

Author(s): Valcic O, Jovanovic IB, Milanovic S

Affiliation(s): Faculty of Veterinary Medicine, University of Belgrade, Department of Physiology and Biochemistry, Bulevar Oslobodjenja 18, 11000 Belgrade, Serbia. olja@vet.bg.ac.rs

Publication date & source: 2011-08, Jpn J Vet Res., 59(2-3):69-77.

Publication type: Randomized Controlled Trial; Research Support, Non-U.S. Gov't

The objective of this experiment was to compare the efficiencies of sodium selenite (SS) and selenized yeast (SY) supplemented at different doses (0.05 and 0.30 mg Se/kg feed) with respect to plasma glutathione peroxidase (Gpx) activity, extent of oxidative lipid injury, and thyroid hormone activation in broilers during the first four weeks of growth. Results indicate a significant increase in plasma Gpx activity and reduction in thiobarbituric acid reactive substances (TBARS) in all supplemented groups at 4 weeks of age compared to 2-week-old chicks. Plasma thyronine activation was highest in SY supplemented broilers. It can be concluded that in the first 4 weeks of broiler life selenite has a more efficient antioxidative effect which is reflected in lower plasma and liver TBARS values. However, broiler feed supplementation with selenized yeast results in a more proficient conversion of T4 to T3.