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[Peridural application of ropivacaine and clonidine for pain therapy after prostatectomy]

Author(s): Voje M, Manohin A

Affiliation(s): Onkologisches Institut in Ljubljana, Zaloska 2, 1000 Ljubljana, Slowenien. minca.voje@gmail.com

Publication date & source: 2008-12, Schmerz., 22(6):672-8.

Publication type: English Abstract

OBJECTIVE: The aim of this study was to find out if ropivacaine with clonidine can be successfully used after radical retropubic prostatectomy. MATERIAL AND METHODS: A total of 86 patients were randomized into two groups each consisting of 43 patients. Patients in group 1 received epidural bupivacaine/morphine/clonidine and those in group 2 ropivacaine and clonidine. If necessary analgesic, antiemetic or antihistamine drugs were administered. Pain on a visual analogue scale (VAS), motoric and sensoric disturbances, sedation, itching, nausea and vomiting, hypotension, need of antihistamines, naloxon, antiemetics, ephedrine, and analgesics were also documented. RESULTS: Differences in sedation, itching, nausea and vomiting, motoric and sensoric disturbances, need of antihistamines, antiemetics, and ketoprofen were significant, the other parameters did not show any significant differences. CONCLUSIONS: We recommend the use of ropivacaine with clonidine in the postoperative pain management after radical retropubic prostatectomy.

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