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[Observation on curative effect of chronic ulcerative colitis treated by retention enema with combination of Chinese and Western drugs]

Author(s): Wang XY, Wu Y, Jiang XM

Affiliation(s): Department of Gastroenterology, Affiliated Hospital of Jiangsu University.

Publication date & source: 2007-12, Zhongguo Zhong Xi Yi Jie He Za Zhi., 27(12):1123-5.

Publication type: English Abstract; Randomized Controlled Trial

OBJECTIVE: To evaluate the effect of retention enema with combination of Chinese and Western drugs in treating chronic ulcerative colitis (CUC). METHODS: The therapeutic effects of retention enema with combination of Chinese and Western drugs (as tested group) and with Western drugs alone (as control group) were compared in a randomized controlled trial. RESULTS: The total effective rate of clinical curative in the tested group and the control group was 96.7% and 73.3% respectively, the difference between them was significant (chi2 = 4.71, P < 0.05). Statistical difference in comparing pre- and post-treatment condition and comparing between groups was shown in comparison of symptoms, scores of endoscopic picture (except that of polypus), and routine examination of stool (except pus cell number, all P < 0.05). The total recurrence rate of the tested group was 33.3% and the control group 60.0%, the difference between them was significant (chi2 = 4.286, P < 0.05). CONCLUSION: Retention enema with combination of Chinese and Western drugs has good curative effects in treating CUC.

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