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Successful treatment of ventriculostomy-related meningitis caused by vancomycin-resistant Enterococcus with intravenous and intraventricular quinupristin/dalfopristin.

Author(s): Williamson JC, Glazier SS, Peacock JE Jr

Affiliation(s): Department of Pharmacy, Wake Forest University Baptist Medical Center, Medical Center Boulevard, Winston-Salem, NC 27157, USA. johnwill@wfubmc.edu

Publication date & source: 2002-01, Clin Neurol Neurosurg., 104(1):54-6.

Publication type: Case Reports

We report a case of ventriculostomy-related meningitis caused by vancomycin-resistant Enterococcus faecium (VRE). The patient was successfully treated with administration of quinupristin/dalfopristin by both intravenous and intraventricular routes. A brief review of the literature is provided, which indicates that optimal management with quinupristin/dalfopristin should include daily intraventricular doses of at least 2 mg.

Page last updated: 2006-01-31

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