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Active ingredient: Acyclovir - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C8H11N5O3

Chemical Name

2-amino-9-(2-hydroxyethoxymethyl)-3H-purin-6-one

Chemical Structure

Molecular Weight

225.205 g/mol

Physical State

Solid

Melting Point

256.5 - 257 oC

Water Solubility

3.399 mg/L

Isoelectric Point

Not Available

Organisms Affected

Human herpes virus

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
NameDNA polymerase (human herpes simplex virus 1)
Gene NameUL30
SynonymsDNA polymerase; EC 2.7.7.7
General FunctionReplication, recombination and repair
Pathwaymap00230 Purine metabolism map00240 Pyrimidine metabolism map03030 DNA polymerase
Reactiondeoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)

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