Chemisty and Biological Activity
Chemical Formula
C21H31N5O2
Chemical Name
8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9- dione
Chemical Structure
Molecular Weight
385.503 g/mol
Physical State
Solid
Melting Point
201.5-202.5oC
Water Solubility
21.4 mg/L
Isoelectric Point
Not Available
Organisms Affected
Humans and other mammals
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
CYP3A4
Primary Drug Target
Name | 5-HT-1A Receptor | Gene Name | HTR1A | Synonyms | 5-hydroxytryptamine 1A receptor; 5-HT-1A; Serotonin receptor 1A; 5- HT1A; G-21 | General Function | Signal transduction and cell communication | Specific Function | This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity |
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