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Active ingredient: Carisoprodol - Brands, Medical Use, Clinical Data

Brands, Medical Use, Clinical Data

Drug Category

  • Muscle Relaxants
  • Skeletal Muscle Relaxants

Dosage Forms

  • Talets

Brands / Synonyms

Apesan; Arusal; Atonalyt; Brianil; Calenfa; Caprodat; Carisol; Carisoma; Carisoprodate; Carisoprodatum; Carisoprodol and Aspirin; Carlsodol; Carlsoma; Carlsoprol; Carsodal; Carsodol; Coprobate; Diolene; Domarax; Flexal; Flexartal; Flexartel; Flibol E; Isobamate; Isomeprobamate; Isopropyl Meprobamate; Isoprotan; Isoprotane; Isoprothane; Izoprotan; Mediquil; Meprobamate; Meprocon; Mioartrina; Miolisodal; Miolisodol; Mioratrina; Mioril; Mioriodol; Nospasm; RELA; Relasom; Relax; Sanoma; Skutamil; Soma; Soma Compound with Codeine; Somadril; Somalgit; Somanil; Stialgin; Tonolyt Isopropyl Meprobamate

Indications

For the relief of discomfort associated with acute, painful, musculoskeletal conditions.

Pharmacology

Carisoprodol is used as a skeletal muscle relaxant. One of its metabolites, meprobamate, is available as an anxiolytic agent.

Mechanism of Action

The mechanism of action is not known. Rather than acting directly on skeletal muscle, carisoprodol interrupts neuronal communication within the reticular formation and spinal cord, resulting in sedation and alteration in pain perception.

Absorption

Not Available

Toxicity

Symptoms of overdose include drowsiness, giddiness, nausea, indigestion, or rash. Other adverse effects attributed to therapeutic use of carisoprodol include dizziness, irritability, insomnia, diplopia, temporary loss of vision, ataxia, weakness, headache, and dysarthria. Non-CNS adverse effects include gastrointestinal complaints, tachycardia, and postural hypotension. Patients sensitive to sulfites or tartrazine may experience wheezing, allergic rashes including erythema multiforme, or anaphylaxis after using some preparations of carisoprodol which contain such additives

Biotrnasformation / Drug Metabolism

hepatic

Contraindications

Acute intermittent porphyria as well as allergic or idiosyncratic reactions to carisoprodol or related compounds, such as meprobamate, mebutamate, or tybamate.

Drug Interactions

No information provided.

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