Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
Not Available
Primary Drug Target
Name
Na+/K+/2Cl- co-transporter
Gene Name
SLC12A1
Synonyms
Solute carrier family 12, member 1; Bumetanide-sensitive sodium-; Potassium-chloride cotransporter 2; Kidney-specific Na-K-Cl symporter
Specific Function
Electrically silent transporter system. Mediates sodium and chloride reabsorption. Plays a vital role in the regulation of ionic balance and cell volume.