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Active ingredient: Citalopram - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C20H21FN2O

Chemical Name

1-(3-dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5- carbonitrile

Chemical Structure

Molecular Weight

324.392 g/mol

Physical State

Solid

Melting Point

182-183oC

Water Solubility

31 mg/L

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP2C19

Primary Drug Target
Nameserotonin uptake pump
Gene NameSLC6A4
SynonymsSodium-dependent serotonin transporter; 5HT transporter; 5HTT
General FunctionTransport activities
Specific FunctionTerminates the action of serotonine by its high affinity sodium-dependent reuptake into presynaptic terminals

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