Chemisty and Biological Activity
Chemical Formula
C18H21NO3
Chemical Name
(5(,6()-7,8-didehydro-4,5-epoxy-3-methoxy-17-methylmorphinan-6-ol
Chemical Structure
Molecular Weight
299.364 g/mol
Physical State
solid
Melting Point
154 - 156 oC
Water Solubility
<0.1 g/100 mL
Isoelectric Point
8.21
Organisms Affected
Humans and other mammals
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
CYP2D6
Primary Drug Target
| Name | Opioid mu Receptor (OP3) | | Gene Name | OPRM1 | | Synonyms | Mu-type opioid receptor; MOR-1 | | Specific Function | Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for beta-endorphin. |
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