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Active ingredient: Dutasteride - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula


Chemical Name

Not Available

Chemical Structure

Molecular Weight

528.53 g/mol

Physical State


Melting Point

Not Available

Water Solubility

Not Available

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)


Primary Drug Target
Name5-alpha reductase 1
Gene NameSRD5A1
Synonyms3-oxo-5-alpha-steroid 4-dehydrogenase 1; EC; Steroid 5- alpha-reductase 1; SR type 1; S5AR
Specific FunctionConverts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5- alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology
Pathwaymap00120 Bile acid biosynthesis map00150 Androgen and estrogen metabolism
Reactiona 3-oxo-5 alpha-steroid + acceptor = a 3-oxo-delta 4-steroid + reduced acceptor

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