Active ingredient: Dutasteride - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C27H30F6N2O2

Chemical Name

Not Available

Chemical Structure

Molecular Weight

528.53 g/mol

Physical State

Solid

Melting Point

Not Available

Water Solubility

Not Available

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP3A4

Primary Drug Target

Name	5-alpha reductase 1
Gene Name	SRD5A1
Synonyms	3-oxo-5-alpha-steroid 4-dehydrogenase 1; EC 1.3.99.5; Steroid 5- alpha-reductase 1; SR type 1; S5AR
Specific Function	Converts testosterone into 5-alpha-dihydrotestosterone and progesterone or corticosterone into their corresponding 5- alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology
Pathway	map00120 Bile acid biosynthesis map00150 Androgen and estrogen metabolism
Reaction	a 3-oxo-5 alpha-steroid + acceptor = a 3-oxo-delta 4-steroid + reduced acceptor