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Active ingredient: Estradiol - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C18H24O2

Chemical Name

13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17- diol

Chemical Structure

Molecular Weight

272.382 g/mol

Physical State

Solid

Melting Point

173-179 oC

Water Solubility

3.6 mg/L

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP1A2

Primary Drug Target
NameEstrogen Receptor
Gene NameESR1
SynonymsEstrogen receptor; ER; Estradiol receptor; ER-alpha
General FunctionRegulation and cellular proliferation
Specific FunctionNuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues

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