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Active ingredient: Fluoxetine - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C17H18F3NO

Chemical Name

N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]-propan-1-amine

Chemical Structure

Molecular Weight

309.326 g/mol

Physical State

Solid

Melting Point

179-182oC

Water Solubility

50 mg/mL at 25°C

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

CYP2C9

Primary Drug Target
Nameserotonin uptake pump
Gene NameSLC6A4
SynonymsSodium-dependent serotonin transporter; 5HT transporter; 5HTT
General FunctionGeneral function prediction only
Specific FunctionTerminates the action of serotonine by its high affinity sodium-dependent reuptake into presynaptic terminals

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