DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Active ingredient: Hydrochlorothiazide - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula


Chemical Name

9-chloro-5,5-dioxo-5^6-thia-2,4-diazabicyclo[4.4.0]deca-6,8,10- triene-8-sulfonamide

Chemical Structure

Molecular Weight

297.741 g/mol

Physical State


Melting Point

274 oC

Water Solubility

0.7 mg/mL

Isoelectric Point


Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
NameThiazide-sensitive sodium-chloride cotransporter
Gene NameSLC12A3
SynonymsSolute carrier family 12, member 3; Thiazide-sensitive sodium-chloride cotransporter; Na-Cl symporter
General FunctionInorganic ion transport and metabolism
Specific FunctionElectrically silent transporter system. Mediates sodium and chloride reabsorption

-- advertisement -- The American Red Cross
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017