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Active ingredient: Ivermectin - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C48H74O14

Chemical Name

Not Available

Chemical Structure

Molecular Weight

875.10 g/mol

Physical State

Solid

Melting Point

155 oC

Water Solubility

Insoluble

Isoelectric Point

Not Available

Organisms Affected

Parasitic nematodes and other roundworms

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
NameGABA-A receptor subunit
Gene NameZC482.1
SynonymsNone
General FunctionSignal transduction and cell-cell communication
Specific FunctionGABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel

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