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Active ingredient: Ketamine - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C13H16ClNO

Chemical Name

2-(2-chlorophenyl)-2-methylamino-cyclohexan-1-one

Chemical Structure

Molecular Weight

237.725 g/mol

Physical State

Solid

Melting Point

92.5 oC

Water Solubility

Not Available

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
NameGlutamate [NMDA] receptor
Gene NameGRIN3A
SynonymsGlutamate [NMDA] receptor subunit 3A precursor; N-methyl-D-aspartate receptor subtype NR3A; NMDAR-L
Specific FunctionNMDA receptor subtype of glutamate-gated ion channels with reduced single-channel conductance, low calcium permeability and low voltage-dependent sensitivity to magnesium. Mediated by glycine. May play a role in the development of dendritic spines. May play a role in PPP2CB-NMDAR mediated signaling mechanism

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