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Active ingredient: Loracarbef - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula


Chemical Name

8-(2-amino-2-phenyl-acetyl)amino-4-chloro-7-oxo-6-azabicyclo[4.2.0]oct-4- ene-5-carboxylic acid

Chemical Structure

Molecular Weight

349.769 g/mol

Physical State


Melting Point

Not Available

Water Solubility

Not Available

Isoelectric Point

Not Available

Organisms Affected

Many kinds of gram-negative and gram-positive eubacteria

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
NamePenicillin Binding Protein
Gene NamepbpA
SynonymsPenicillin-binding proteins 1A/1B
General FunctionCell wall/membrane/envelope biogenesis
Specific FunctionPenicillin bindig proteins are nvolved in the final transpeptidation step during the synthesis of peptidoglycan. They are also called transpeptidases. They take the D-alanyl-D-alanine moiety and cap off the synthesis of peptidoglycan with this peptide moiety.

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