Chemisty and Biological Activity
Chemical Formula
C16H16ClN3O4
Chemical Name
8-(2-amino-2-phenyl-acetyl)amino-4-chloro-7-oxo-6-azabicyclo[4.2.0]oct-4- ene-5-carboxylic acid
Chemical Structure
Molecular Weight
349.769 g/mol
Physical State
Solid
Melting Point
Not Available
Water Solubility
Not Available
Isoelectric Point
Not Available
Organisms Affected
Many kinds of gram-negative and gram-positive eubacteria
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
Not Available
Primary Drug Target
| Name | Penicillin Binding Protein | | Gene Name | pbpA | | Synonyms | Penicillin-binding proteins 1A/1B | | General Function | Cell wall/membrane/envelope biogenesis | | Specific Function | Penicillin bindig proteins are nvolved in the final transpeptidation step during
the synthesis of peptidoglycan. They are also called transpeptidases. They
take the D-alanyl-D-alanine moiety and cap off the synthesis of peptidoglycan
with this peptide moiety. |
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