Chemisty and Biological Activity
Chemical Formula
C17H19NO3
Chemical Name
(5α,6α)-Didehydro-4,5-epoxy-17-methylmorphinan-3,6-diol
Chemical Structure
Molecular Weight
285.338 g/mol
Physical State
Solid
Melting Point
255oC (sulfate salt)
Water Solubility
149 mg/L (60 mg/mL for sulfate salt)
Isoelectric Point
8.21
Organisms Affected
Humans and other mammals
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
CYP2D6
Primary Drug Target
| Name | Mu-type opioid receptor | | Gene Name | OPRM1 | | Synonyms | MOR-1 | | General Function | Signal transduction, cell-cell communication | | Specific Function | Inhibits neurotransmitter release by reducing calcium ion currents and
increasing potassium ion conductance. Receptor for beta-endorphin |
|
