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Active ingredient: Naltrexone - Chemisty and Biological Activity

Chemisty and Biological Activity

Chemical Formula

C20H23NO4

Chemical Name

Not Available

Chemical Structure

Molecular Weight

341.401 g/mol

Physical State

Solid

Melting Point

169-170 oC (274-276 oC for hydrochloride salt)

Water Solubility

100 mg/mL (as hydrochloride salt)

Isoelectric Point

Not Available

Organisms Affected

Humans and other mammals

Phase 1 Metabolising Enzyme (1-st Step of Metabolism)

Not Available

Primary Drug Target
NameOpioid mu Receptor (OP3)
Gene NameOPRM1
SynonymsMu-type opioid receptor; MOR-1
Specific FunctionInhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Receptor for beta-endorphin

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