Chemisty and Biological Activity
Chemical Formula
C13H20N6O4
Chemical Name
2-[(2-amino-6-oxo-3,9-dihydropurin-9-yl)methoxy]ethyl2-amino-3-methyl- butanoate
Chemical Structure
Molecular Weight
324.336 g/mol
Physical State
Solid
Melting Point
Not Available
Water Solubility
Not Available
Isoelectric Point
Not Available
Organisms Affected
Human herpes virus
Phase 1 Metabolising Enzyme (1-st Step of Metabolism)
Not Available
Primary Drug Target
Name | Thymidine Kinase | Gene Name | TK | Synonyms | Thymidine kinase; EC 2.7.1.21 | Specific Function | In latent infection, may allow the virus to be reactivated and to grow in cells lacking a high concentration of phosphorylated nucleic acid precursors, such as nerve cells that do not replicate their genome | Pathway | map00240 Pyrimidine metabolism | Reaction | ATP + thymidine = ADP + thymidine 5'-phosphate |
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