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Acetadote (Acetylcysteine Injection) - Drug Interactions, Contraindications, Overdosage, etc

 
 



DRUG INTERACTIONS

No drug-drug interaction studies have been conducted.

OVERDOSAGE

Single intravenous doses of acetylcysteine at 1000 mg/kg in mice, 2445 mg/kg in rats, 1500 mg/kg in guinea pigs, 1200 mg/kg in rabbits and 500 mg/kg in dogs were lethal. Symptoms of acute toxicity were ataxia, hypoactivity, labored respiration, cyanosis, loss of righting reflex and convulsions.

CONTRAINDICATIONS

Acetadote is contraindicated in patients with previous anaphylactoid reactions to acetylcysteine.

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