Ancef (Cefazolin Sodium) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

The following reactions have been reported:

Gastrointestinal

Diarrhea, oral candidiasis (oral thrush), vomiting, nausea, stomach cramps, anorexia, and pseudomembranous colitis. Onset of pseudomembranous colitis symptoms may occur during or after antibiotic treatment (see WARNINGS). Nausea and vomiting have been reported rarely.

Allergic

Anaphylaxis, eosinophilia, itching, drug fever, skin rash, Stevens-Johnson syndrome.

Hematologic

Neutropenia, leukopenia, thrombocytopenia, thrombocythemia.

Hepatic

Transient rise in SGOT, SGPT, and alkaline phosphatase levels has been observed. As with other cephalosporins, reports of hepatitis have been received.

Renal

As with other cephalosporins, reports of increased BUN and creatinine levels, as well as renal failure, have been received.

Local Reactions

Rare instances of phlebitis have been reported at site of injection. Pain at the site of injection after intramuscular administration has occurred infrequently. Some induration has occurred.

Other Reactions

Genital and anal pruritus (including vulvar pruritus, genital moniliasis, and vaginitis).

REPORTS OF SUSPECTED ANCEF SIDE EFFECTS / ADVERSE REACTIONS

Possible Ancef side effects / adverse reactions in 23 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2011-10-19

Patient: 23 year old female weighing 76.7 kg (168.6 pounds)

Reactions: LIP Swelling, Vomiting, Nausea, Mouth Ulceration, Vision Blurred, Pyrexia, Rash Maculo-Papular, Arthropod Bite

Adverse event resulted in: hospitalization

Suspect drug(s):
Ancef

Other drugs received by patient: Diphenhydramine HCL; Triamcinolone Topical Cream; Unasyn; Synthroid; Tylenol-500; Cefirizine; Oxycodone HCL; Insuline Aspart; Sodium Chloride Nasal 0.65% Solution; Hydrocortisone; Famotidine

Possible Ancef side effects / adverse reactions in 86 year old male

Reported by a pharmacist from United States on 2012-01-10

Patient: 86 year old male weighing 68.0 kg (149.6 pounds)

Reactions: Pruritus, Rash

Suspect drug(s):
Protonix
    Dosage: 40 mg q day iv
    Indication: Gastrointestinal Disorder Postoperative
    Start date: 2011-10-04
    End date: 2011-10-06

Protonix
    Dosage: 40 mg q day iv
    Indication: Prophylaxis
    Start date: 2011-10-04
    End date: 2011-10-06

Ancef
    Dosage: 1gm q8 iv
    Indication: Postoperative Care
    Start date: 2011-10-04
    End date: 2011-10-06

Ancef
    Dosage: 1gm q8 iv
    Indication: Prophylaxis
    Start date: 2011-10-04
    End date: 2011-10-06

Other drugs received by patient: Metoclopramide; Mercapurine

Possible Ancef side effects / adverse reactions in 69 year old female

Reported by a pharmacist from United States on 2012-03-05

Patient: 69 year old female

Reactions: Haemolytic Anaemia

Adverse event resulted in: hospitalization

Suspect drug(s):
Ancef

Other drugs received by patient: Ranitidine