BENZACLIN SUMMARY
BenzaClin® Topical Gel contains clindamycin phosphate, (7(S)-chloro-7-deoxylincomycin-2-phosphate). Clindamycin phosphate is a water soluble ester of the semi-synthetic antibiotic produced by a 7(S)-chloro-substitution of the 7(R)-hydroxyl group of the parent antibiotic lincomycin.
BenzaClin Topical Gel is indicated for the topical treatment of acne vulgaris.
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NEWS HIGHLIGHTSMedia Articles Related to Benzaclin (Clindamycin Topical)
Health Tip: Four Common Types Of Acne
Source: MedicineNet Acne Specialty [2017.09.20]
Title: Health Tip: Four Common Types Of Acne
Category: Health News
Created: 9/20/2017 12:00:00 AM
Last Editorial Review: 9/20/2017 12:00:00 AM
Acne (Pimples) Quiz: Test Your Medical IQ
Source: MedicineNet Acne Specialty [2017.09.19]
Title: Acne (Pimples) Quiz: Test Your Medical IQ
Category: MedicineNet Quiz
Created: 2/28/2011 4:15:00 PM
Last Editorial Review: 9/19/2017 5:39:39 PM
Skin Quiz: Acne, Dry Skin, Dandruff & More
Source: MedicineNet Acne Specialty [2017.09.19]
Title: Skin Quiz: Acne, Dry Skin, Dandruff & More
Category: MedicineNet Quiz
Created: 10/7/2010 12:00:00 AM
Last Editorial Review: 9/19/2017 5:01:04 PM
Health Tip: Can't Clear Your Acne?
Source: MedicineNet Acne Specialty [2017.08.02]
Title: Health Tip: Can't Clear Your Acne?
Category: Health News
Created: 8/2/2017 12:00:00 AM
Last Editorial Review: 8/2/2017 12:00:00 AM
Acne 101: Types, Best Treatments, Medication, Cystic Acne
Source: MedicineNet isotretinoin Specialty [2017.05.04]
Title: Acne 101: Types, Best Treatments, Medication, Cystic Acne
Category: Slideshows
Created: 10/16/2014 12:00:00 AM
Last Editorial Review: 5/4/2017 12:00:00 AM
Published Studies Related to Benzaclin (Clindamycin Topical)
Efficacy of clindamycin in reducing pain following tonsillectomy in adults: a
double-blind, randomised trial. [2013]
reducing throat pain after tonsillectomy in adult patients... CONCLUSION: Topical clindamycin was not demonstrated to be more effective than
Topical 4% nicotinamide vs. 1% clindamycin in moderate inflammatory acne
vulgaris. [2013]
Nicotinamide and clindamycin gels are two popular topical medications for acne
vulgaris... Skin type is a significant factor in choosing
between topical nicotinamide and clindamycin in patients with acne vulgaris.
Fitzpatrick skin types and clindamycin phosphate 1.2%/benzoyl peroxide gel:
efficacy and tolerability of treatment in moderate to severe acne. [2012]
efficacy of acne medications in skin of color... CONCLUSIONS: Acne subjects with Fitzpatrick skin types IV-VI were not found to be
Treatment of moderate to severe acne vulgaris in a Hispanic population: a
post-hoc analysis of efficacy and tolerability of clindamycin phosphate
1.2%/benzoyl peroxide 2.5% gel. [2012]
in Hispanics... CONCLUSIONS: Overall efficacy and tolerability with clindamycin phosphate
A randomized, double-blind, placebo-controlled, pilot study to assess the
efficacy and safety of clindamycin 1.2% and tretinoin 0.025% combination gel for
the treatment of acne rosacea over 12 weeks. [2012]
rosacea after 12 weeks of usage... CONCLUSIONS: A combination gel of clindamycin phosphate 1.2% and tretinoin 0.025%
Clinical Trials Related to Benzaclin (Clindamycin Topical)
Evaluation of Quality of Life, Efficacy, and Tolerance of Duac� Gel Compared to Differin� Gel in the Treatment of Acne [Completed]
The objectives of this clinical trial are to compare the quality of life of the subjects,
the efficacy and the tolerance of Duac® Gel (gel formulation with a combination of
clindamycin phosphate [equivalent to 1% clindamycin] and 5% benzoyl peroxide), applied once
daily, against Differin® Gel (gel with 0. 1% adapalene), used once daily, in the treatment of
mild to moderate acne vulgaris.
Evaluation of the Effectiveness, Safety, and Tolerability of Duac Akne Gel and Epiduo Gel in the Treatment of Facial Acne Vulgaris [Completed]
The purpose of this study is to compare the effectiveness of two marketed products in
subjects with facial acne vulgaris
To Compare the Efficacy and Safety of Clindamycin Phosphate 1.2% / Benzoyl Peroxide 5% Gel of CHL Versus DUAC® Gel [Recruiting]
This is an Randomized, Double-blind, Multicentric, Parallel-group, Active and Placebo
Controlled, Three Arm Clinical Study.
The main objective is to evaluate bioequivalence of Test formulation (Clindamycin Phosphate
1. 2%/Benzoyl peroxide 5% gel) of Cadila Healthcare with Reference formulation (DUAC® Gel of
Stiefel Laboratories)in the ratio of 2: 2:1 of Test drug, Reference drug and Placebo
respectively.
Total study duration will be for a period of 78 days which includes treatment duration of 77
days.
850 subjects will be enrolled (randomized)as per the inclusion and exclusion criteria
mentioned in the protocol.
A Study Comparing Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel to Duac� Topical Gel in the Treatment of Acne Vulgaris [Completed]
The objective of this study is to compare the relative efficacy and safety of the test
formulation Clindamycin 1%/Benzoyl Peroxide 5% Topical Gel (Taro Pharmaceuticals Inc.) to
the marketed formulation Duac® Topical Gel (Clindamycin 1%/Benzoyl Peroxide 5%) (Stiefel) in
the treatment of the inflamed lesions of acne vulgaris. Both the test and reference
formulations will also be compared to a placebo formulation to test for superiority.
Study Comparing Clindamycin Phosphate and Benzoyl Peroxide Gel to Acanya® Gel and Both to a Vehicle Control in the Treatment of Acne Vulgaris [Completed]
The objective of this study is to compare the safety and efficacy profiles of Taro
Pharmaceutical Inc.'s Clindamycin Phosphate and Benzoyl Peroxide Gel 1. 2%/2. 5% to Acanya®
(Clindamycin Phosphate and Benzoyl Peroxide) Gel, 1. 2%/2. 5% and to demonstrate the superior
efficacy of the two active formulations over that of the vehicle in the treatment of acne
vulgaris.
Reports of Suspected Benzaclin (Clindamycin Topical) Side Effects
Colitis Ulcerative (4),
Gastrointestinal Haemorrhage (2),
Drug Ineffective (2),
Loss of Consciousness (2),
Oesophageal Ulcer (2),
Anaemia (2),
Odynophagia (2),
Small Intestinal Obstruction (2),
Diarrhoea (2),
Leukocytosis (2), more >>
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PATIENT REVIEWS / RATINGS / COMMENTSBased on a total of 3 ratings/reviews, Benzaclin has an overall score of 8. The effectiveness score is 8.67 and the side effect score is 7.33. The scores are on ten point scale: 10 - best, 1 - worst.
| | Benzaclin review by 28 year old female patient | | | Rating |
| Overall rating: | |   |
| Effectiveness: | | Highly Effective |
| Side effects: | | Mild Side Effects | | |
Treatment Info |
| Condition / reason: | | acne |
| Dosage & duration: | | dont remember (dosage frequency: twice a day) for the period of 1 year |
| Other conditions: | | acne scarring |
| Other drugs taken: | | nothing | | |
Reported Results |
| Benefits: | | None |
| Side effects: | | None |
| Comments: | | None |
|
| | Benzaclin review by 40 year old female patient | | | Rating |
| Overall rating: | | |
| Effectiveness: | | Considerably Effective |
| Side effects: | | Mild Side Effects | | |
Treatment Info |
| Condition / reason: | | acne |
| Dosage & duration: | | topical application (dosage frequency: once daily) for the period of several years |
| Other conditions: | | none |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | This has helped reduce my cystic acne that forms on my chin area. Nothing has helped previously.I had tried OTC products including Proactiv as well as RX differin. The cysts still occur occasionally but with far less frequency. |
| Side effects: | | dryness |
| Comments: | | Applied daily in the evening. At first sign of a cyst forming I usually apply it twice daily. |
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| | Benzaclin review by 40 year old female patient | | | Rating |
| Overall rating: | | |
| Effectiveness: | | Considerably Effective |
| Side effects: | | Mild Side Effects | | |
Treatment Info |
| Condition / reason: | | acne |
| Dosage & duration: | | topical application (dosage frequency: once daily) for the period of several years |
| Other conditions: | | none |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | This has helped reduce my cystic acne that forms on my chin area. Nothing has helped previously.I had tried OTC products including Proactiv as well as RX differin. The cysts still occur occasionally but with far less frequency. |
| Side effects: | | dryness |
| Comments: | | Applied daily in the evening. At first sign of a cyst forming I usually apply it twice daily. |
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Page last updated: 2017-09-20
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