DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Celestone Soluspan (Betamethasone Acetate / Betamethasone Sodium Phosphate Injection) - Side Effects and Adverse Reactions



Anaphylactoid reaction, anaphylaxis, angioedema.


Bradycardia, cardiac arrest, cardiac arrhythmias, cardiac enlargement, circulatory collapse, congestive heart failure, fat embolism, hypertension, hypertrophic cardiomyopathy in premature infants, myocardial rupture following recent myocardial infarction (see WARNINGS), pulmonary edema, syncope, tachycardia, thromboembolism, thrombophlebitis, vasculitis.


Acne, allergic dermatitis, cutaneous and subcutaneous atrophy, dry scaly skin, ecchymoses and petechiae, edema, erythema, hyperpigmentation, hypopigmentation, impaired wound healing, increased sweating, rash, sterile abscess, striae, suppressed reactions to skin tests, thin fragile skin, thinning scalp hair, urticaria.


Decreased carbohydrate and glucose tolerance, development of cushingoid state, glucosuria, hirsutism, hypertrichosis, increased requirements for insulin or oral hypoglycemic adrenocortical and pituitary unresponsiveness (particularly in times of stress, as in trauma, surgery, or illness), suppression of growth in pediatric patients.


Congestive heart failure in susceptible patients, fluid retention, hypokalemic alkalosis, potassium loss, sodium retention.


Abdominal distention, bowel/bladder dysfunction (after intrathecal administration), elevation in serum liver enzyme levels (usually reversible upon discontinuation), hepatomegaly, increased appetite, nausea, pancreatitis, peptic ulcer with possible perforation and hemorrhage, perforation of the small and large intestine (particularly in patients with inflammatory bowel disease), ulcerative esophagitis.


Negative nitrogen balance due to protein catabolism.


Aseptic necrosis of femoral and humeral heads, calcinosis (following intra-articular or intralesional use), Charcot-like arthropathy, loss of muscle mass, muscle weakness, osteoporosis, pathologic fracture of long bones, postinjection flare (following intra-articular use), steroid myopathy, tendon rupture, vertebral compression fractures.


Convulsions, depression, emotional instability, euphoria, headache, increased intracranial pressure with papilledema (pseudotumor cerebri) usually following discontinuation of treatment, insomnia, mood swings, neuritis, neuropathy, paresthesia, personality changes, psychic disorders, vertigo. Arachnoiditis, meningitis, paraparesis/paraplegia, and sensory disturbances have occurred after intrathecal administration (see WARNINGS, Neurologic section).


Exophthalmos, glaucoma, increased intraocular pressure, posterior subcapsular cataracts, rare instances of blindness associated with periocular injections.


Abnormal fat deposits, decreased resistance to infection, hiccups, increased or decreased motility and number of spermatozoa, malaise, moon face, weight gain.



Below is a sample of reports where side effects / adverse reactions may be related to Celestone Soluspan. The information is not vetted and should not be considered as verified clinical evidence.

Possible Celestone Soluspan side effects / adverse reactions in 48 year old female

Reported by a physician from South Africa on 2011-12-01

Patient: 48 year old female

Reactions: Hypersensitivity, Feeling Hot, Paraesthesia

Adverse event resulted in: life threatening event, hospitalization

Suspect drug(s):
Celestone Soluspan
    Dosage: 2 ml; im
    Indication: Inflammation
    Start date: 2011-09-13

Celestone Soluspan
    Dosage: 2 ml; im
    Indication: Carpal Tunnel Syndrome
    Start date: 2011-09-13

Possible Celestone Soluspan side effects / adverse reactions in 57 year old female

Reported by a consumer/non-health professional from United States on 2012-02-23

Patient: 57 year old female weighing 90.7 kg (199.6 pounds)

Reactions: Respiratory Rate Increased, Dyspnoea, Dehydration, Heart Rate Increased

Adverse event resulted in: life threatening event

Suspect drug(s):
Celestone Soluspan

See index of all Celestone Soluspan side effect reports >>

Drug label data at the top of this Page last updated: 2013-06-10

-- advertisement -- The American Red Cross
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017