Chlorphen Mal Pseudoeph (Chlorpheniramine Maleate / Pseudoephedrine Hydrochloride) - Summary

SUMMARY

Chlorphen Mal/Pseudoeph HCl 0.8/9 mg Drops is an antihistaminic and decongestant drop for oral administration.

Chlorphen Mal/Pseudoeph HCl 0.8/9 mg Drops is indicated for symptomatic relief of upper respiratory symptoms, including nasal congestion, associated with allergy or the common cold.

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NEWS HIGHLIGHTS

Media Articles Related to Chlorphen Mal Pseudoeph (Chlorpheniramine / Pseudoephedrine)

It's a Food Allergy! Where's the School Nurse?
Source: MedicineNet Allergy Specialty [2017.09.18]
Title: It's a Food Allergy! Where's the School Nurse?
Category: Health News
Created: 9/18/2017 12:00:00 AM
Last Editorial Review: 9/18/2017 12:00:00 AM

Nasal Irrigation: Natural Relief for Cold & Allergy Symptoms
Source: MedicineNet Allergy Specialty [2017.09.12]
Title: Nasal Irrigation: Natural Relief for Cold & Allergy Symptoms
Category: Slideshows
Created: 1/28/2010 12:30:00 PM
Last Editorial Review: 9/12/2017 12:00:00 AM

The Best Way to Diagnose a Food Allergy
Source: MedicineNet Allergy Specialty [2017.09.08]
Title: The Best Way to Diagnose a Food Allergy
Category: Health News
Created: 9/8/2017 12:00:00 AM
Last Editorial Review: 9/8/2017 12:00:00 AM

Peanut Allergy Pill Works Four Years Later
Source: MedicineNet Food Allergy Specialty [2017.08.21]
Title: Peanut Allergy Pill Works Four Years Later
Category: Health News
Created: 8/18/2017 12:00:00 AM
Last Editorial Review: 8/21/2017 12:00:00 AM

Does Your Child Really Have a Food Allergy?
Source: MedicineNet Food Allergy Specialty [2017.07.25]
Title: Does Your Child Really Have a Food Allergy?
Category: Health News
Created: 7/24/2017 12:00:00 AM
Last Editorial Review: 7/25/2017 12:00:00 AM

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Clinical Trials Related to Chlorphen Mal Pseudoeph (Chlorpheniramine / Pseudoephedrine)

Study of AHIST in Seasonal Allergic Rhinitis Patients [Withdrawn]
Objectives: A) To gather pharmacodynamic measurements and assess blood levels of the active ingredients in AHIST over the dosage interval period of 12 hours. Hypothesis: Hysteresis curves plotting each active ingredient's blood levels over a 12-hour dosage interval will substantiate S5 Symptom Diary scores (IE: evidentiary therapeutic window data); B) To report subjective scores by subjects rating the efficacy of a single dose AHIST in relieving nasal congestion, rhinorrhea, nasal itching, sneezing, and post-nasal drip over a 12-hour dosage interval. Hypothesis: Greater than 66% of subjects will document clinically significant relief over a 12-hour period from one dose of AHIST; C) Report any side effects or adverse drug reactions and rate the severity of any incidence. Hypothesis: Not more than one patient will have an adverse event significant enough to warrant withdrawal; side effects will be mild with the most frequently reported side effect occurring in less than 10% of patients—drowsiness.

Fed Study of Chlorpheniramine Polistirex and Hydrocodone Polistirex Capsules and Tussionex� Pennkinetic� Extended Release Oral Suspension [Completed]
The objective of this open-label, randomized, two-period, crossover study was to evaluate the oral bioavailability of the Mallinckrodt extended release test capsule formulation of chlorpheniramine polistirex/hydrocodone polistirex compared to an equivalent oral dose of a commercially available extended release oral suspension of chlorpheniramine polistirex/hydrocodone polistirex (Tussionex® Pennkinetic® Extended Release Oral Suspension, Celltech Pharmaceuticals, Inc.) in a test group of healthy subjects under fed conditions.

Study Evaluating Chlorpheniramine Maleate Liquid in Children and Adolescents [Completed]

Fasting Study of Chlorpheniramine Polistirex and Hydrocodone Polistirex Capsules and Tussionex� Pennkinetic� Extended Release Oral Suspension [Completed]
The objective of this open-label, randomized, two-period, crossover study was to evaluate the oral bioavailability of the Mallinckrodt extended release test capsule formulation of chlorpheniramine polistirex/hydrocodone polistirex compared to an equivalent oral dose of a commercially available extended release oral suspension of chlorpheniramine polistirex/hydrocodone polistirex (Tussionex® Pennkinetic® Extended Release Oral Suspension, Celltech Pharmaceuticals, Inc.) in a test group of healthy subjects under fasting conditions.

StahistRx Phase 2, Five-arm, Parallel Group, Active vs Active, Double-blind Study [Active, not recruiting]
This active vs active comparative trial will evaluate the safety and efficacy of incremental doses of atropine in combination with pseudoephedrine 120 mg/chlorpheniramine 8 mg in adult patients with a history of seasonal allergic rhinitis. Hypotheses are defined by total nasal symptom scores (TNSS) recorded by subjects in diaries where efficacy will be established by statistical significance where p < 0. 05.

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