DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Chlorthalidone (Chlorthalidone) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

The following adverse reactions have been observed, but there is not enough systematic collection of data to support an estimate of their frequency.

Gastrointestinal System Reactions: anorexia, gastric irritation, nausea, vomiting, cramping, diarrhea, constipation, jaundice (intrahepatic cholestatic jaundice), pancreatitis.

Central Nervous System Reactions: dizziness, vertigo, paresthesias, headache, xanthopsia.

Hematologic Reactions: leukopenia, agranulocytosis, thrombocytopenia, aplastic anemia.

Dermatologic-Hypersensitivity Reactions: purpura, photosensitivity, rash, urticaria, necrotizing angiitis (vasculitis, cutaneous vasculitis), Lyell's syndrome (toxic epidermal necrolysis).

Cardiovascular Reactions: orthostatic hypotension may occur and may be aggravated by alcohol, barbiturates, or narcotics.

Other Adverse Reactions: hyperglycemia, glycosuria, hyperuricemia, muscle spasm, weakness, restlessness, impotence.

Whenever adverse reactions are moderate or severe, chlorthalidone dosage should be reduced or therapy withdrawn.



REPORTS OF SUSPECTED CHLORTHALIDONE SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Chlorthalidone. The information is not vetted and should not be considered as verified clinical evidence.

Possible Chlorthalidone side effects / adverse reactions in 68 year old female

Reported by a health professional (non-physician/pharmacist) from Spain on 2011-10-07

Patient: 68 year old female

Reactions: Confusional State, Muscular Weakness, Delirium, Hypokalaemia, Lethargy

Suspect drug(s):
Tramadol HCL
    Start date: 2011-04-13
    End date: 2011-04-18

Xeloda
    Indication: Gastric Cancer
    Start date: 2011-04-01

Furosemide
    Indication: Cardiac Failure Congestive
    Start date: 2011-04-13
    End date: 2011-04-18

Chlorthalidone
    Dosage: 50 mg,
    Administration route: Oral
    Indication: Hypertension
    Start date: 2011-04-01
    End date: 2011-04-18

Morphine
    Indication: Pain
    Start date: 2011-04-13
    End date: 2011-04-18

Other drugs received by patient: Lisinopril



Possible Chlorthalidone side effects / adverse reactions in 68 year old female

Reported by a health professional (non-physician/pharmacist) from Spain on 2011-10-11

Patient: 68 year old female

Reactions: Confusional State, Muscular Weakness, Delirium, Lethargy, Hypokalaemia

Adverse event resulted in: hospitalization

Suspect drug(s):
Chlorthalidone
    Administration route: Oral
    Indication: Hypertension
    Start date: 2011-04-01
    End date: 2011-04-18

Tramadol HCL
    Indication: Pain
    Start date: 2011-04-13
    End date: 2011-04-18

Furosemide
    Indication: Cardiac Failure Congestive
    Start date: 2011-04-13
    End date: 2011-04-18

Xeloda
    Indication: Gastric Cancer
    Start date: 2011-04-01

Morphine
    Indication: Pain
    Start date: 2011-04-13
    End date: 2011-04-18

Other drugs received by patient: Lisinopril



Possible Chlorthalidone side effects / adverse reactions in 88 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2011-10-18

Patient: 88 year old female

Reactions: Blood Pressure Increased, Haemoglobin Decreased, Presyncope, Blood Potassium Increased, Nodal Rhythm, Bradycardia, Blood Creatinine Increased

Adverse event resulted in: hospitalization

Suspect drug(s):
Metoprolol Tartrate
    Dosage: 50 mg, bid

Hydralazine HCL
    Dosage: 50 mg, bid

Lisinopril
    Dosage: 40 mg, unk

Diltiazem HCL
    Dosage: 180 mg, unk

Chlorthalidone
    Dosage: 25 mg, unk

Clonidine
    Dosage: 0.3 mg, weekly patch



See index of all Chlorthalidone side effect reports >>

Drug label data at the top of this Page last updated: 2009-08-31

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017