CIALIS SUMMARY
CIALIS (tadalafil) is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5).
Erectile Dysfunction
CIALIS® is indicated for the treatment of erectile dysfunction (ED).
Benign Prostatic Hyperplasia
CIALIS is indicated for the treatment of the signs and symptoms of benign prostatic hyperplasia (BPH).
Erectile Dysfunction and Benign Prostatic Hyperplasia
CIALIS is indicated for the treatment of ED and the signs and symptoms of BPH (ED/BPH).
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NEWS HIGHLIGHTSMedia Articles Related to Cialis (Tadalafil)
Narrow Networks Get Tighter for Mental Health Specialists
Source: Medscape Business of Medicine Headlines [2017.09.26]
If you've got a plan offered on the federal health insurance marketplace and you're looking for a therapist, you may have to look hard: The average provider network includes only 11% of all the mental health care providers in a given market, according to a recent study.
Kaiser Health News
Cardiologist Care in Hospital Yields Better HFpEF Outcomes
Source: theheart.org | Medscape Cardiology Headlines [2017.09.28]
Specialist in-hospital care of patients with preserved-EF heart failure was more aggressive than with generalists, and follow-up cardiologist visits more likely, even at a major medical center.
Medscape Medical News
Published Studies Related to Cialis (Tadalafil)
Urodynamic effects of the combination of tamsulosin and daily tadalafil in men
with lower urinary tract symptoms secondary to benign prostatic hyperplasia: a
randomized, placebo-controlled clinical trial. [2013]
study (UDS)... CONCLUSIONS: The association of tamsulosin/tadalafil reduces detrusor pressure at
The role of initial success rates and other factors in determining reliability of
outcomes of phosphodiesterase inhibitor therapy for erectile dysfunction: a
pooled analysis of 17 placebo-controlled trials of tadalafil for use as needed. [2013]
Profile questions 2 and 3... CONCLUSIONS: The findings affirm the reliability of successful outcomes with
Tadalafil once daily and extracorporeal shock wave therapy in the management of patients with Peyronie's disease and erectile dysfunction: results from a prospective randomized trial. [2011.11.15]
Extracorporeal shock wave therapy improves erectile function in patients with Peyronie's disease. However, erectile dysfunction still persists in many cases... In conclusion extracorporeal shock wave therapy plus tadalafil 5 mg once daily may represent a valid conservative strategy for the management of patients with Peyronie's disease and erectile dysfunction.
Efficacy and safety of tadalafil once daily in the treatment of men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia: results of an international randomized, double-blind, placebo-controlled trial. [2011.11]
BACKGROUND: Tadalafil is being investigated for the treatment of lower urinary tract symptoms (LUTS) suggestive of benign prostatic hyperplasia (BPH-LUTS). OBJECTIVE: To assess efficacy, including onset, and safety of tadalafil on BPH-LUTS and the subject's and clinician's perception of changes in urinary symptoms... CONCLUSIONS: Tadalafil 5mg once daily for 12 wk resulted in a clinically meaningful reduction in total IPSS results as early as 1 wk and achieved statistical significance at 4 wk in men with BPH-LUTS. The adverse event profile was consistent with that previously reported in men with ED. TRIAL REGISTRATION: This clinical trial is registered on the clinicaltrials.gov website (http://www.clinicaltrials.gov). The registration number is NCT00827242. Copyright (c) 2011. Published by Elsevier B.V.
Clinical efficacy of phosphodiesterase-5 inhibitor tadalafil in Eisenmenger syndrome--a randomized, placebo-controlled, double-blind crossover study. [2011.09]
OBJECTIVES: In a randomized double-blind crossover trial, we compared the efficacy of phosphodiesterase-5 (PDE-5) inhibitor tadalafil with placebo in patients of Eisenmenger Syndrome (ES). The primary end point was the change in 6-minute walk test distance (6 MWD). Secondary end points were the effect of the drug on systemic oxygen saturation (SO(2) ), pulmonary vascular resistance (PVR), systemic vascular resistance (SVR), effective pulmonary blood flow (EPBF), and World Health Organization (WHO) functional class. BACKGROUND: ES is a disorder with limited treatment options. Uncontrolled studies have shown PDE-5 inhibitors to be beneficial in patients of ES... CONCLUSION: In this first short-term placebo-controlled trial of tadalafil in patients of ES, the drug was well tolerated and significantly improved exercise capacity, functional class, SO(2) , and pulmonary hemodynamics. (c) 2011 Copyright the Authors. Congenital Heart Disease (c) 2011 Wiley Periodicals, Inc.
Clinical Trials Related to Cialis (Tadalafil)
Study of Tadalafil for the Treatment of Diabetic Patients With Symptoms of Upset Stomach and Delayed Stomach Emptying [Completed]
The purposes of this study are to determine whether an experimental drug known as tadalafil
can reduce symptoms of dyspepsia (fullness after eating, inability to finish a regular meal,
bloating, discomfort or pain in the upper abdomen, belching after meals, nausea, vomiting)
in diabetic patients, and/or reduce the amount of time the stomach takes to empty the
contents of a standard meal. The safety of tadalafil given once daily for 8 weeks in this
population will also be studied.
A Clinical Trial of Ambrisentan and Tadalafil in Pulmonary Arterial Hypertension Associated With Systemic Sclerosis [Active, not recruiting]
This will be a 36-week, randomized, double-blind, parallel group study comparing the effects
of tadalafil monotherapy, ambrisentan monotherapy and combination therapy with tadalafil
and ambrisentan in patients with PAH-SSc. Standard outcome measures such as six-minute walk
distance (6MWD), NYHA classification, and hemodynamic measurements will be assessed, as well
as novel functional measures of RV-PV function including the transthoracic echocardiogram
parameter tricuspid annular plane systolic ejection (TAPSE), contrast-enhanced cardiac MRI
and heart rate variability assessed by Holter monitoring. This design (excluding a
placebo-placebo arm) was selected for ethical concerns and to provide optimal efficiency and
active therapy to all study subjects. It also allows for comparisons between the two
monotherapies and with combination therapy.
Study of Tadalafil Once-a Day for 12 Weeks in Men With Signs and Symptoms of Benign Prostatic Hyperplasia [Completed]
This is a randomized, double-blind, placebo-controlled, parallel-design, multinational,
12-week study to compare the efficacy, dose response, and safety of tadalafil once a day
versus placebo in men with signs and symptoms of benign prostatic hyperplasia, including
lower urinary tract symptoms.
PHIRST-1: Tadalafil in the Treatment of Pulmonary Arterial Hypertension [Completed]
Study the Safety and Effectiveness of Tadalafil on High Blood Pressure in the Blood Vessel Going From the Heart to the Lungs [Completed]
Study to determine the long term safety of tadalafil in patients with increased blood
pressure in the blood vessel that carries blood from the right heart to the lungs and to see
if it will keep the disease from getting worse.
Reports of Suspected Cialis (Tadalafil) Side Effects
Drug Ineffective (58),
Vision Blurred (41),
Headache (28),
Visual Impairment (24),
Intentional Drug Misuse (23),
Myalgia (18),
Back Pain (18),
Wrong Technique in Drug Usage Process (17),
Nausea (14),
Blindness (14), more >>
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PATIENT REVIEWS / RATINGS / COMMENTSBased on a total of 7 ratings/reviews, Cialis has an overall score of 8.71. The effectiveness score is 9.43 and the side effect score is 8. The scores are on ten point scale: 10 - best, 1 - worst. Below are selected reviews: the highest, the median and the lowest rated.
| | Cialis review by 59 year old male patient | | | Rating |
| Overall rating: | |  |
| Effectiveness: | | Highly Effective |
| Side effects: | | No Side Effects | | |
Treatment Info |
| Condition / reason: | | impotence |
| Dosage & duration: | | 20mg taken 5 days for the period of 5 days |
| Other conditions: | | none |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | Cialis taken as prescribed. Had immediate postitive effect as promised, strong, long-lasting erection. Intercourse possible for long period of time- approx 2 days. Had no side-effects at all. Am very satisfied and recommend. |
| Side effects: | | No side effects at all. No headache, gastro-intestinal disturbances or other. |
| Comments: | | Took tadalafil 20 mg in the evening after meal. Had erection approx 30 min later. Erection lasted for 2 days- had never experienced such long-lasting erection. |
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| | Cialis review by 44 year old male patient | | | Rating |
| Overall rating: | |  |
| Effectiveness: | | Highly Effective |
| Side effects: | | Mild Side Effects | | |
Treatment Info |
| Condition / reason: | | erectile disfunction |
| Dosage & duration: | | 5mg (quater of 20mg tab) taken 1-2 times a week for the period of 3 months |
| Other conditions: | | none |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | Very quck and long lasting erection. Have been able to have sexual intercorse for 2-3 days no problem. That also had a psychological effect of easing anxiety. |
| Side effects: | | some headache and face flashing |
| Comments: | | 5mg was taken 1-2 times a week for several months. That produced very strong and lasting erection in about 20-30 mins. Taking cialis also had the psychological effect of easing anxiety. |
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| | Cialis review by 53 year old male patient | | | Rating |
| Overall rating: | | |
| Effectiveness: | | Highly Effective |
| Side effects: | | Moderate Side Effects | | |
Treatment Info |
| Condition / reason: | | ED |
| Dosage & duration: | | 20 mg taken as needed for the period of two weeks |
| Other conditions: | | none |
| Other drugs taken: | | none | | |
Reported Results |
| Benefits: | | Long lasting erection |
| Side effects: | | achy joints similar to flu symptoms during the next couple of days after taking. Not bad, but definitely annoying. Aspirin helps relieve, but I did not like having to take a pill to counteract another pill. I do not have the same symptom with Viagra. |
| Comments: | | Taken as needed for ED. It is effective in as little as 30 minutes. Time depends if taken on empty stomach or after a meal. |
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Page last updated: 2017-09-28
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