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Clobevate (Clobetasol Propionate Topical) - Indications and Dosage



Clobevate is a super-high potency corticosteroid formulation indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Treatment beyond 2 consecutive weeks is not recommended, and the total dosage should not exceed 50 g per week because of the potential for the drug to suppress the hypothalamic-pituitary-adrenal (HPA) axis. Use in children under 12 years of age is not recommended.


Apply a thin layer of Clobevate to the affected areas twice daily and rub in gently and completely (see INDICATIONS AND USAGE).

Clobevate is a super-high potency topical corticosteroid; therefore, treatment should be limited to 2 consecutive weeks, and amounts greater than 50 g per week should not be used.

As with other highly active corticosteroids, therapy should be discontinued when control has been achieved. If no improvement is seen within 2 weeks, reassessment of diagnosis may be necessary.

Clobevate should not be used with occlusive dressings.


Clobevate (Clobetasol Propionate Gel) 0.05% is supplied in 45-g (NDC 0145-2790-04) tubes.

Store between 15° and 30°C (59° and 86°F). Clobevate should not be refrigerated.

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