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Collagenase Santyl (Collagenase) - Published Studies


Published Studies Related to Collagenase Santyl

Well-designed clinical trials related to Collagenase Santyl

Clinical efficacy, safety and tolerability of collagenase clostridium histolyticum for the treatment of peyronie disease in 2 large double-blind, randomized, placebo controlled phase 3 studies. [2013]

Injectable collagenase Clostridium histolyticum: a new nonsurgical treatment for Dupuytren's disease. [2010.12]

Collagenase injection as nonsurgical treatment of Dupuytren's disease: 8-year follow-up. [2010.04]

Percutaneous treatment of non-contained lumbar disc herniation by injection of oxygen-ozone combined with collagenase. [2009.12]

Effect of collagenase and esterase on resin-dentin interface: a comparative study between a total-etch adhesive and a self-etch adhesive. [2009.10]

Injectable collagenase clostridium histolyticum for Dupuytren's contracture. [2009.09.03]

Effect of smoking, abstention, and nicotine patch on epidermal healing and collagenase in skin transudate. [2009.05]

Efficacy and safety of injectable mixed collagenase subtypes in the treatment of Dupuytren's contracture. [2007.07]

Well-designed clinical trials possibly related to Collagenase Santyl

Effects of N-acetylcysteine on the cardiac remodeling biomarkers and major adverse events following acute myocardial infarction: a randomized clinical trial. [2014]

The effect of prolonged systemic doxycycline therapy on serum tissue degrading proteinases in coronary bypass patients: a randomized, double-masked, placebo-controlled clinical trial. [2014]

Glyburide is associated with attenuated vasogenic edema in stroke patients. [2014]

Red yeast rice improves lipid pattern, high-sensitivity C-reactive protein, and vascular remodeling parameters in moderately hypercholesterolemic Italian subjects. [2013]

High MMP-9 activity levels in fragile X syndrome are lowered by minocycline. [2013]

Determining clinically important changes in range of motion in patients with Dupuytren's Contracture: secondary analysis of the randomized, double-blind, placebo-controlled CORD I study. [2011.11.01]

The toll-like receptor 4-antagonist eritoran reduces murine cardiac hypertrophy. [2011.06]

Evaluation, using extracted human teeth, of Ricetral as a storage medium for avulsions--an in vitro study. [2011.06]

Clinical and biochemical efficacy of minocycline in nonsurgical periodontal therapy: a randomized controlled pilot study. [2011.06]

Continuous peripheral neural blockade to alleviate signs of experimentally induced severe forelimb pain in horses. [2011.04.15]

The developmental and acute phases of insulin-induced laminitis involve minimal metalloproteinase activity. [2011.04.15]

The effect of subantimicrobial-dose-doxycycline periodontal therapy on serum biomarkers of systemic inflammation: a randomized, double-masked, placebo-controlled clinical trial. [2011.03]

The effect of low-level laser therapy as an adjunct to non-surgical periodontal treatment. [2011.03]

Efficacy and tolerance of enzymatic hydrolysed collagen (EHC) vs. glucosamine sulphate (GS) in the treatment of knee osteoarthritis (KOA). [2011.03]

A randomized placebo controlled trial of the effect of preoperative statin use on matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in areas of low and peak wall stress in patients undergoing elective open repair of abdominal aortic aneurysm. [2011.01]

Tomato paste rich in lycopene protects against cutaneous photodamage in humans in vivo: a randomized controlled trial. [2011.01]

Regular consumption of vitamin D-fortified yogurt drink (Doogh) improved endothelial biomarkers in subjects with type 2 diabetes: a randomized double-blind clinical trial. [2011]

Efficacy of the pan-selectin antagonist Bimosiamose on ozone-induced airway inflammation in healthy subjects--a double blind, randomized, placebo-controlled, cross-over clinical trial. [2011]

The effect of subantimicrobial-dose-doxycycline periodontal therapy on serum biomarkers of systemic inflammation: a randomized, double-masked, placebo-controlled clinical trial. [2011]

Comparative effects of rosuvastatin and allopurinol on circulating levels of matrix metalloproteinases and tissue inhibitors of metalloproteinases in patients with chronic heart failure. [2010.12.03]

Anesthetic technique and the cytokine and matrix metalloproteinase response to primary breast cancer surgery. [2010.11]

Effects of telmisartan on markers of ventricular remodeling in patients with acute myocardial infarction: comparison with enalapril. [2010.11]

Adjunctive treatment of chronic periodontitis with daily dietary supplementation with omega-3 Fatty acids and low-dose aspirin. [2010.11]

Effect of smoking, smoking cessation, and nicotine patch on wound dimension, vitamin C, and systemic markers of collagen metabolism. [2010.11]

[Effect of percutaneous coronary intervention timing and cilostazol use on left ventricular remodeling in patients with non-ST elevation myocardial infarction]. [2010.10]

Maternal serum interleukin-6, C-reactive protein, and matrix metalloproteinase-9 concentrations as risk factors for preterm birth <32 weeks and adverse neonatal outcomes. [2010.09]

Effect of Tianhuang Granule on intracranial pressure and serum matrix metalloproteinase-9 in patients with acute cerebral hemorrhage. [2010.08]

Association of polymorphisms of zinc metalloproteinases with clinical response to stem cell therapy. [2010.08]

A short-term evaluation of Nd:YAG laser as an adjunct to scaling and root planing in the treatment of periodontal inflammation. [2010.08]

Effects of scaling and root planing and subantimicrobial dose doxycycline on gingival crevicular fluid levels of matrix metalloproteinase-8, -13 and serum levels of HsCRP in patients with chronic periodontitis. [2010.08]

The impact of vitamin C supplementation in pregnancy and in vitro upon fetal membrane strength and remodeling. [2010.07]

Evaluation of the lipid lowering ability, anti-inflammatory effects and clinical safety of intensive therapy with Zhibitai, a Chinese traditional medicine. [2010.07]

A phase I/II dose-escalation trial of vitamin D3 and calcium in multiple sclerosis. [2010.06.08]

Matrix metalloproteinase-9 is increased in obese subjects and decreases in response to pioglitazone. [2010.06]

Use of a specific MMP-inhibitor (galardin) for preservation of hybrid layer. [2010.06]

Changes of matrix metalloproteinase-9 level is associated with left ventricular remodeling following acute myocardial infarction among patients treated with trandolapril, valsartan or both. [2010.06]

Changes of matrix metalloproteinase-9 level is associated with left ventricular remodeling following acute myocardial infarction among patients treated with trandolapril, valsartan or both. [2010.05.25]

Anti-wrinkle activity of Platycarya strobilacea extract and its application as a cosmeceutical ingredient. [2010.05]

Exercise ameliorates serum MMP-9 and TIMP-2 levels in patients with type 2 diabetes. [2010.04]

Moderate Champagne consumption promotes an acute improvement in acute endothelial-independent vascular function in healthy human volunteers. [2010.04]

Pleiotropic effects of atorvastatin on monocytes in atherosclerotic patients. [2010.03]

Serum concentrations of matrix metalloproteinase-9, tissue inhibitor of matrix metalloproteinase-1 and alpha2-macroglobulin in healthy subjects after supplementation with different doses of marine n-3 fatty acids. [2010.02.25]

Rosiglitazone reduces plasma levels of inflammatory and hemostatic biomarkers and improves global endothelial function in habitual heavy smokers without diabetes mellitus or metabolic syndrome. [2010.02]

Association of gingival crevicular fluid biomarkers during periodontal maintenance with subsequent progressive periodontitis. [2010.02]

Clinical and biochemical characteristics after intra-articular injection for the treatment of osteoarthritis of the knee: prospective randomized study of sodium hyaluronate and corticosteroid. [2010.01]

Effects of inhaled corticosteroids on metalloproteinase-8 and tissue inhibitor of metalloproteinase-1 in the airways of asthmatic children. [2010]

Preventive effect of commercial desensitizing toothpastes on bovine enamel erosion in vitro. [2010]

Differential effects of low-dose and high-dose beta-carotene supplementation on the signs of photoaging and type I procollagen gene expression in human skin in vivo. [2010]

Adjunctive treatment of chronic periodontitis with daily dietary supplementation with omega-3 Fatty acids and low-dose aspirin. [2010]

Pleiotropic effects of atorvastatin on monocytes in atherosclerotic patients. [2010]

A role for plasma transforming growth factor-beta and matrix metalloproteinases in aortic aneurysm surveillance in Marfan syndrome? [2010]

Red ginseng root extract mixed with Torilus fructus and Corni fructus improves facial wrinkles and increases type I procollagen synthesis in human skin: a randomized, double-blind, placebo-controlled study. [2009.12]

Effects of chemical cross-linkers on caries-affected dentin bonding. [2009.12]

Serum inflammatory mediators in pregnancy: changes after periodontal treatment and association with pregnancy outcomes. [2009.11]

Effect of rosiglitazone, metformin and medical nutrition treatment on arterial stiffness, serum MMP-9 and MCP-1 levels in drug naive type 2 diabetic patients. [2009.10]

Dexamethasone, cerebrospinal fluid matrix metalloproteinase concentrations and clinical outcomes in tuberculous meningitis. [2009.09.30]

Clinical efficacy of two-phase leukocyte filtration in high-risk patients undergoing coronary revascularization with cardiopulmonary bypass. [2009.09]

Mechanical properties of tannic-acid-treated dentin matrix. [2009.09]

MEK4 function, genistein treatment, and invasion of human prostate cancer cells. [2009.08.19]

A prospective, randomised, placebo-controlled study to identify biomarkers associated with active treatment in psoriatic arthritis: effects of adalimumab treatment on synovial tissue. [2009.08]

[Effects of probucol, aspirin and atorvastatin combination therapy upon atherosclerosis] [2009.07.28]

Serum levels of MMP-9 and TIMP-1 in primary hypertension and effect of antihypertensive treatment. [2009.07]

E-selectin, interleukin 18, serum amyloid a, and matrix metalloproteinase 9 are associated with clinical response to golimumab plus methotrexate in patients with active rheumatoid arthritis despite methotrexate therapy. [2009.07]

Long-term weight loss decreases the nontraditional cardiovascular risk factors interleukin-18 and matrix metalloproteinase-9 in obese subjects. [2009.07]

High-dose squalene ingestion increases type I procollagen and decreases ultraviolet-induced DNA damage in human skin in vivo but is associated with transient adverse effects. [2009.06]

Left ventricular remodeling after acute myocardial infarction: does eplerenone have an effect? [2009.06]

Effects of doxycycline on serum and endometrial levels of MMP-2, MMP-9 and TIMP-1 in women using a levonorgestrel-releasing subcutaneous implant. [2009.06]

Simvastatin reduces OX40 and OX40 ligand expression in human peripheral blood mononuclear cells and in patients with atherosclerotic cerebral infarction. [2009.05]

Increased systemic and myocardial expression of neutrophil gelatinase-associated lipocalin in clinical and experimental heart failure. [2009.05]

Neoadjuvant radiochemotherapy increases matrix metalloproteinase activity in healthy tissue in esophageal cancer patients. [2009.05]

Clinical trial of doxycycline for matrix metalloproteinase-9 inhibition in patients with an abdominal aneurysm: doxycycline selectively depletes aortic wall neutrophils and cytotoxic T cells. [2009.04.28]

[Effect of tongmal recipe on atherosclerosis in patients with early lower extremity arteriopathy caused by type 2 diabetes mellitus] [2009.04]

Course of matrix metalloproteinase-9 isoforms after the administration of uric acid in patients with acute stroke: a proof-of-concept study. [2009.04]

Anti-inflammatory effects of salmeterol/fluticasone, tiotropium/fluticasone or tiotropium in COPD. [2009.04]

Expansion of small-diameter abdominal aortic aneurysms is not reflected by the release of inflammatory mediators IL-6, MMP-9 and CRP in plasma. [2009.04]

Doxycycline therapy for abdominal aneurysm: Improved proteolytic balance through reduced neutrophil content. [2009.03]

[Isoflurane preconditioning decreases the plasma concentration of matrix metalloproteinase-9 and protects myocardium against cardiopulmonary bypass in cardiac valve replacement]. [2009.02]

Self-etching increases matrix metalloproteinase expression in the dentin-pulp complex. [2009.01]

Dysregulated RANK ligand/RANK axis in hyperhomocysteinemic subjects: effect of treatment with B-vitamins. [2009.01]

Inflammatory, lipid, thrombotic, and genetic markers of coronary heart disease risk in the women's health initiative trials of hormone therapy. [2008.11.10]

Metabolic syndrome in postmenopausal women: the influence of oral or transdermal estradiol on inflammation and coagulation markers. [2008.11]

A randomized, placebo-controlled trial of doxycycline after endoluminal aneurysm repair. [2008.09]

Inhibition of MMP2/MMP9 after spinal cord trauma reduces apoptosis. [2008.08.01]

Comparison effect of atorvastatin (10 versus 80 mg) on biomarkers of inflammation and oxidative stress in subjects with metabolic syndrome. [2008.08.01]

Subantimicrobial-Dose Doxycycline Modulates Gingival Crevicular Fluid Biomarkers of Periodontitis in Postmenopausal Osteopenic Women. [2008.08]

Guided tissue regeneration may modulate gene expression in periodontal intrabony defects: a human study. [2008.08]

Plasma matrix metalloproteinase-9 levels and blood pressure in short children born small for gestational age and effects of growth hormone treatment. [2008.08]

Effect of soy nuts on adhesion molecules and markers of inflammation in hypertensive and normotensive postmenopausal women. [2008.07.01]

Effect of intensive atorvastatin therapy on prostaglandin E2 levels and metalloproteinase-9 activity in the plasma of patients with non-ST-elevation acute coronary syndrome. [2008.07.01]

The role of topical negative pressure in wound repair: expression of biochemical markers in wound fluid during wound healing. [2008.07]

[Preventive and therapeutic effect of E-leng capsule on post-operation recurrence of ovarian endometriotic cysts and its influence on expression of matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase-1 in eutopic and ectopic endometrium] [2008.06]

Value of fibrosis markers for staging liver fibrosis in patients with precirrhotic alcoholic liver disease. [2008.06]

Comparison of renal and vascular protective effects between telmisartan and amlodipine in hypertensive patients with chronic kidney disease with mild renal insufficiency. [2008.05]

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