DrugLib.com — Drug Information Portal

Rx drug information, pharmaceutical research, clinical trials, news, and more

Demerol (Meperidine Hydrochloride) - Side Effects and Adverse Reactions

 
 



ADVERSE REACTIONS

The major hazards of meperidine, as with other narcotic analgesics, are respiratory depression and, to a lesser degree, circulatory depression; respiratory arrest, shock, and cardiac arrest have occurred.

The most frequently observed adverse reactions include lightheadedness, dizziness, sedation, nausea, vomiting, and sweating. These effects seem to be more prominent in ambulatory patients and in those who are not experiencing severe pain. In such individuals, lower doses are advisable. Some adverse reactions in ambulatory patients may be alleviated if the patient lies down.

Other adverse reactions include:

Nervous System. Euphoria, dysphoria, weakness, headache, agitation, tremor, uncoordinated muscle movements, severe convulsions, transient hallucinations and disorientation, visual disturbances. Inadvertent injection about a nerve trunk may result in sensory-motor paralysis which is usually, though not always, transitory.

Gastrointestinal. Dry mouth, constipation, biliary tract spasm.

Cardiovascular. Flushing of the face, tachycardia, bradycardia, palpitation, hypotension (see WARNINGS ), syncope, phlebitis following intravenous injection.

Genitourinary. Urinary retention.

Allergic. Pruritus, urticaria, other skin rashes, wheal and flare over the vein with intravenous injection.

Other. Pain at injection site; local tissue irritation and induration following subcutaneous injection, particularly when repeated; antidiuretic effect.



REPORTS OF SUSPECTED DEMEROL SIDE EFFECTS / ADVERSE REACTIONS

Below is a sample of reports where side effects / adverse reactions may be related to Demerol. The information is not vetted and should not be considered as verified clinical evidence.

Possible Demerol side effects / adverse reactions in 67 year old female

Reported by a pharmacist from United States on 2011-10-06

Patient: 67 year old female weighing 66.0 kg (145.2 pounds)

Reactions: Bradycardia

Adverse event resulted in: hospitalization

Suspect drug(s):
Versed
    Dosage: 1mg once iv recent
    Indication: Preoperative Care

Versed
    Dosage: 1mg once iv recent
    Indication: Gastrostomy Tube Insertion

Demerol
    Dosage: 50mg once iv recent
    Indication: Preoperative Care

Demerol
    Dosage: 50mg once iv recent
    Indication: Gastrostomy Tube Insertion

Other drugs received by patient: Lipitor; Lisinopril; Aggrenox; Potassium Chloride; Coreg



Possible Demerol side effects / adverse reactions in 89 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2011-10-26

Patient: 89 year old male

Reactions: Drug Dose Omission, Wrong Technique in Drug Usage Process, Pain, Withdrawal Syndrome

Adverse event resulted in: hospitalization

Suspect drug(s):
Demerol



Possible Demerol side effects / adverse reactions in 73 year old male

Reported by a health professional (non-physician/pharmacist) from United States on 2011-10-26

Patient: 73 year old male weighing 71.7 kg (157.7 pounds)

Reactions: Agitation, Confusional State, Vomiting, Nausea, Chills, Abnormal Behaviour, Disorientation, Aggression, Dizziness, Oxygen Saturation Decreased, Infusion Related Reaction

Adverse event resulted in: hospitalization

Suspect drug(s):
Ativan
    Dosage: 1 mg, single
    Indication: Nausea
    Start date: 2011-10-13
    End date: 2011-10-13

Ativan
    Dosage: 1 mg, single
    Indication: Vomiting
    Start date: 2011-10-13
    End date: 2011-10-13

Provenge
    Dosage: 250 ml, single, intravenous
    Indication: Prostate Cancer Metastatic
    Start date: 2011-09-29
    End date: 2011-09-29

Provenge
    Dosage: 250 ml, single, intravenous
    Indication: Prostate Cancer Metastatic
    Start date: 2011-09-15
    End date: 2011-09-15

Provenge

Demerol
    Dosage: 25 mg,
    Indication: Chills
    Start date: 2011-10-13
    End date: 2011-10-13

Other drugs received by patient: Metoprolol Tartrate; Glipizide; Aspirin; Lisinopril; Metformin HCL; Aspirin; Omeprazole



See index of all Demerol side effect reports >>

Drug label data at the top of this Page last updated: 2011-08-23

-- advertisement -- The American Red Cross
 
Home | About Us | Contact Us | Site usage policy | Privacy policy

All Rights reserved - Copyright DrugLib.com, 2006-2017