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Depakene (Valproic Acid) - Published Studies

 
 



Depakene Related Published Studies

Well-designed clinical trials related to Depakene (Valproic Acid)

Valproic acid, valproate and divalproex in the maintenance treatment of bipolar disorder. [2013]

Effect of D: -cycloserine and valproic acid on the extinction of reinstated fear-conditioned responses and habituation of fear conditioning in healthy humans: a randomized controlled trial. [2011.12]

Prolonged survival with valproic acid use in the EORTC/NCIC temozolomide trial for glioblastoma. [2011.09.20]

Evaluation of the subjective and reinforcing effects of diphenhydramine, levetiracetam, and valproic acid. [2011.06]

D-cycloserine facilitates procedural learning but not declarative learning in healthy humans: a randomized controlled trial of the effect of D-cycloserine and valproic acid on overnight properties in the performance of non-emotional memory tasks. [2011.05]

Effect of D-cycloserine and valproic acid on the extinction of reinstated fear-conditioned responses and habituation of fear conditioning in healthy humans: a randomized controlled trial. [2011]

SMA CARNI-VAL trial part I: double-blind, randomized, placebo-controlled trial of L-carnitine and valproic acid in spinal muscular atrophy. [2010.08.19]

Interleaved transcranial magnetic stimulation and fMRI suggests that lamotrigine and valproic acid have different effects on corticolimbic activity. [2010.04]

Ethosuximide, valproic acid, and lamotrigine in childhood absence epilepsy. [2010.03.04]

The influence of drug-drug interaction and patients' characteristics on valproic acid's clearance in adults with epilepsy using nonlinear mixed effects modeling. [2009.12.08]

Effect of valproic acid on body weight, food intake, physical activity and hormones: results of a randomized controlled trial. [2009.09]

Randomized sequential trial of valproic acid in amyotrophic lateral sclerosis. [2009.08]

Effects of valproic acid on sleep in children with epilepsy. [2009.08]

Lamotrigine and valproic acid have different effects on motorcortical neuronal excitability. [2009.04]

Effect of valproic acid on body weight, food intake, physical activity and hormones: results of a randomized controlled trial. [2008.06.26]

Lack of pharmacokinetic interaction of levetiracetam on carbamazepine, valproic acid, topiramate, and lamotrigine in children with epilepsy. [2007.11]

Lack of Pharmacokinetic Interaction of Levetiracetam on Carbamazepine, Valproic Acid, Topiramate, and Lamotrigine in Children with Epilepsy. [2007.07.25]

Valproic acid adjunctive therapy for HIV-associated cognitive impairment: a first report. [2006.03.28]

Every-12-hour administration of extended-release divalproex in patients with epilepsy: impact on plasma valproic acid concentrations. [2006.03]

Lower effectiveness of divalproex versus valproic acid in a prospective, quasi-experimental clinical trial involving 9,260 psychiatric admissions. [2005.02]

Quality of life assessment in patients with bipolar disorder treated with olanzapine added to lithium or valproic acid. [2004.09]

Lamotrigine versus valproic acid as first-line monotherapy in newly diagnosed typical absence seizures: an open-label, randomized, parallel-group study. [2004.09]

Treatment of idiopathic restless legs syndrome (RLS) with slow-release valproic acid compared with slow-release levodopa/benserazid. [2004.05]

Valproic acid has no effect on pain in polyneuropathy: a randomized, controlled trial. [2004.01.27]

Valproic acid for agitation in dementia. [2004]

Valproic acid for the treatment of social anxiety disorder. [2003.05]

Lack of pharmacokinetic interaction between valproic acid and a traditional Chinese medicine, Paeoniae Radix, in healthy volunteers. [2000.12]

Influence of Ramadan on the pharmacokinetics of a single oral dose of valproic acid administered at two different times. [2000.03]

The efficacy of felbamate as add-on therapy to valproic acid in the Lennox-Gastaut syndrome. [1999.04]

Effects of switching from Depakene to generic valproic acid on individuals with mental retardation. [1997.12]

Lack of kinetic interaction between valproic acid and citrus pectin. [1997.10]

Pharmacokinetics of valproic acid in patients with juvenile myoclonic epilepsy on monotherapy. [1997.04]

Acute effects of bromocriptine, cyproheptadine, and valproic acid on plasma adrenocorticotropin secretion in Nelson's syndrome. [1997.02]

Valproic acid treatment of learning disorder and severely epileptiform EEG without clinical seizures. [1996.01]

Effect of felbamate on valproic acid disposition in healthy volunteers: inhibition of beta-oxidation. [1996.01]

Relative bioavailability of different valproic acid formulations. [1995.12]

The effect of felbamate on valproic acid disposition. [1994.11]

The pharmacokinetics of oxcarbazepine and its active metabolite 10-hydroxy-carbazepine in healthy subjects and in epileptic patients treated with phenobarbitone or valproic acid. [1993.10]

Pharmacokinetic comparison of two valproic acid formulations--a plain and a controlled release enteric-coated tablets. [1993.08]

Synergy of carbamazepine and valproic acid in affective illness: case report and review of the literature. [1992.08]

Intermittent prophylaxis in febrile convulsions: diazepam or valproic acid? [1990.07]

Prevention of alcohol withdrawal seizures with carbamazepine and valproic acid. [1989.05]

Well-designed clinical trials possibly related to Depakene (Valproic Acid)

Antiepileptic drugs for the primary and secondary prevention of seizures after stroke. [2014]

Genotype variant associated with add-on memantine in bipolar II disorder. [2014]

Effect of pregabalin augmentation in treatment of patients with combat-related chronic posttraumatic stress disorder: a randomized controlled trial. [2014]

Risperidone versus risperidone plus sodium valproate for treatment of bipolar disorders: a randomized, double-blind clinical-trial. [2014]

Comparative efficacy and acceptability of drug treatments for bipolar depression: a multiple-treatments meta-analysis. [2014]

Pretreatment cognitive deficits and treatment effects on attention in childhood absence epilepsy. [2013]

The established status epilepticus trial 2013. [2013]

Add-on memantine to valproate treatment increased HDL-C in bipolar II disorder. [2013]

Assessment of cognitive impairments and seizure characteristics in electroconvulsive therapy with and without sodium valproate in manic patients. [2013]

Characterizing relapse prevention in bipolar disorder with adjunctive ziprasidone: clinical and methodological implications. [2013]

Randomized, placebo-controlled trial of quetiapine XR and divalproex ER monotherapies in the treatment of the anxious bipolar patient. [2013]

Comparing efficacy of ECT with and without concurrent sodium valproate therapy in manic patients. [2012]

Effects of divalproex on smoking cue reactivity and cessation outcomes among smokers achieving initial abstinence. [2012]

The DRD2/ANKK1 gene is associated with response to add-on dextromethorphan treatment in bipolar disorder. [2012]

Asenapine as adjunctive treatment for acute mania associated with bipolar disorder: results of a 12-week core study and 40-week extension. [2012]

A comparative study of the effects of low-dose topiramate versus sodium valproate in migraine prophylaxis. [2012]

Ziprasidone with adjunctive mood stabilizer in the maintenance treatment of bipolar I disorder: long-term changes in weight and metabolic profiles. [2012]

Chronic divalproex sodium use and brain atrophy in Alzheimer disease. [2011.09.27]

Chronic divalproex sodium to attenuate agitation and clinical progression of Alzheimer disease. [2011.08]

Are post intracerebral hemorrhage seizures prevented by anti-epileptic treatment? [2011.08]

Double-blind randomized trial of risperidone versus divalproex in pediatric bipolar disorder: fMRI outcomes. [2011.07.30]

[Observation on therapeutic effect of acupoint catgut-embedding combined western medicine for epilepsy of generalized seizures type]. [2011.06]

Acute efficacy of divalproex sodium versus placebo in mood stabilizer-naive bipolar I or II depression: a double-blind, randomized, placebo-controlled trial. [2011.06]

Magnesium valproate in learning disabled children with interictal paroxysmal EEG patterns: Preliminary report. [2011.04.01]

Efficacy of aripiprazole adjunctive to lithium or valproate in the long-term treatment of patients with bipolar I disorder with an inadequate response to lithium or valproate monotherapy: a multicenter, double-blind, randomized study. [2011.03]

Paliperidone extended-release as adjunctive therapy to lithium or valproate in the treatment of acute mania: a randomized, placebo-controlled study. [2011.03]

Early symptom change and prediction of subsequent remission with olanzapine augmentation in divalproex-resistant bipolar mixed episodes. [2011.02]

Child Mania Rating Scale-Parent Version: a valid measure of symptom change due to pharmacotherapy. [2011.01]

Fasted state bioavailability of two delayed release formulations of divalproex sodium in healthy Iranian volunteers. [2011]

Estimation of resource utilisation difference between lithium and valproate treatment groups from the VALID study. [2011]

Co-morbid disruptive behavior disorder and aggression predict functional outcomes and differential response to risperidone versus divalproex in pharmacotherapy for pediatric bipolar disorder. [2011]

A pilot study of the efficacy and safety of paroxetine augmented with risperidone, valproate, buspirone, trazodone, or thyroid hormone in adult Chinese patients with treatment-resistant major depression. [2011]

Chronic divalproex sodium to attenuate agitation and clinical progression of Alzheimer disease. [2011]

Treatment of suicide attempters with bipolar disorder: a randomized clinical trial comparing lithium and valproate in the prevention of suicidal behavior. [2011]

Symptomatic response to divalproex in subtypes of conduct disorder. [2011]

Efficacy and safety of adjunctive oral ziprasidone for acute treatment of depression in patients with bipolar I disorder: a randomized, double-blind, placebo-controlled trial. [2011]

Are post intracerebral hemorrhage seizures prevented by anti-epileptic treatment? [2011]

Double-blind randomized trial of risperidone versus divalproex in pediatric bipolar disorder: fMRI outcomes. [2011]

Comparative efficacy and acceptability of mood stabilizer and second generation antipsychotic monotherapy for acute mania--a systematic review and meta-analysis. [2011]

Patterns of prescription of antiepileptic drugs in patients with refractory epilepsy at tertiary referral centres in Italy. [2010.10]

Adjunctive armodafinil for major depressive episodes associated with bipolar I disorder: a randomized, multicenter, double-blind, placebo-controlled, proof-of-concept study. [2010.10]

A double-blind, placebo-controlled study with quetiapine as adjunct therapy with lithium or divalproex in bipolar I patients with coexisting alcohol dependence. [2010.10]

Double-blind randomized trial of risperidone versus divalproex in pediatric bipolar disorder. [2010.09]

A randomized add-on trial of an N-methyl-D-aspartate antagonist in treatment-resistant bipolar depression. [2010.08]

Divalproex sodium versus placebo in the treatment of acute bipolar depression: a systematic review and meta-analysis. [2010.08]

Adjunctive armodafinil for major depressive episodes associated with bipolar I disorder: a randomized, multicenter, double-blind, placebo-controlled, proof-of-concept study. [2010.07.27]

Lithium-induced gray matter volume increase as a neural correlate of treatment response in bipolar disorder: a longitudinal brain imaging study. [2010.07]

Divalproex extended-release in acute bipolar II depression. [2010.07]

LICAVAL: combination therapy in acute and maintenance treatment of bipolar disorder. [2010.06.23]

Efficacy of sodium valproate and haloperidol in the management of acute mania: a randomized open-label comparative study. [2010.06]

Randomized, double-blind, placebo-controlled study of divalproex extended release loading monotherapy in ambulatory bipolar spectrum disorder patients with moderate-to-severe hypomania or mild mania. [2010.05]

A randomized, placebo-controlled, multicenter study of divalproex sodium extended-release in the acute treatment of mania. [2010.04]

Valproate for the treatment of acute bipolar depression: systematic review and meta-analysis. [2010.04]

Early predisposition to osteomalacia in Indian adults on phenytoin or valproate monotherapy and effective prophylaxis by simultaneous supplementation with calcium and 25-hydroxy vitamin D at recommended daily allowance dosage: a prospective study. [2010.03]

Efficacy of valproate versus lithium in mania or mixed mania: a randomized, open 12-week trial. [2010.03]

Divalproex sodium vs placebo for the treatment of irritability in children and adolescents with autism spectrum disorders. [2010.03]

Ziprasidone plus a mood stabilizer in subjects with bipolar I disorder: a 6-month, randomized, placebo-controlled, double-blind trial. [2010.02]

Lithium plus valproate combination therapy versus monotherapy for relapse prevention in bipolar I disorder (BALANCE): a randomised open-label trial. [2010.01.30]

Lithium plus valproate combination therapy versus monotherapy for relapse prevention in bipolar I disorder (BALANCE): a randomised open-label trial. [2010.01.30]

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