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Entocort EC (Budesonide) - Summary



Budesonide, the active ingredient of ENTOCORT® EC capsules, is a synthetic corticosteroid.

ENTOCORT EC is indicated for

  • the treatment of mild to moderate active Crohn's disease involving the iluem and/or the ascending colon and
  • the maintenance of clinical remission of mild to moderate Crohn's disease involving the ileum and/or the ascending colon for up to 3 months.

See all Entocort EC indications & dosage >>


Published Studies Related to Entocort EC (Budesonide)

Budesonide foam induces remission in patients with mild to moderate ulcerative proctitis and ulcerative proctosigmoiditis. [2015]
remission in patients with ulcerative proctitis or ulcerative proctosigmoiditis... CONCLUSIONS: Budesonide rectal foam was well tolerated and more efficacious than

Induction of clinical and colonoscopic remission of mild-to-moderate ulcerative colitis with budesonide MMX 9 mg: pooled analysis of two phase 3 studies. [2015]
budesonide MMX in patients with mild-to-moderate active UC... CONCLUSION: This pooled analysis showed that budesonide MMX 9 mg is efficacious,

Effects of nebulized high-dose budesonide on moderate-to-severe acute exacerbation of asthma in children: a randomized, double-blind, placebo-controlled study. [2013]
exacerbation of asthma... CONCLUSION: On the basis of nebulized short-acting bronchodilators, addition of

Safety and Tolerability of High-Dose Budesonide/Formoterol via Turbuhaler(R) in Japanese Patients with Asthma: A Randomized, Double-Blind, Crossover, Active Comparator-Controlled, Phase III Study. [2012.01.01]
Background: The use of budesonide/formoterol as both maintenance and reliever therapy in asthma is recommended in many countries; however, there are limited data available for the Asian patient population. Objective: This study aimed to evaluate the short-term safety and tolerability of a fixed high-dose combination of the inhaled corticosteroid budesonide and the long-acting beta(2)-adrenoceptor agonist formoterol with that of the beta(2)-agonist terbutaline for acute symptom relief in Japanese adults with persistent asthma who were already receiving a combination of budesonide/formoterol maintenance therapy...

Abatacept for Crohn's disease and ulcerative colitis. [2012]
modulator, in Crohn's disease (CD) and ulcerative colitis (UC) is unknown... CONCLUSIONS: The studies showed that abatacept is not efficacious for the

more studies >>

Clinical Trials Related to Entocort EC (Budesonide)

Budesonide in Treating Patients With Lung Nodules at High Risk of Developing Lung Cancer [Completed]
RATIONALE: Chemoprevention is the use of certain drugs to keep cancer from forming, growing, or coming back. The use of budesonide may keep lung cancer from forming in patients with lung nodules. PURPOSE: This randomized phase II trial is studying how well inhalation budesonide works in treating patients with lung nodules who are at high risk of lung cancer.

Acute Airway Vascular Smooth Muscle Effects of Inhaled Budesonide [Completed]
Glucocorticosteroids recently have been shown to have non-genomic actions that are plasma membrane-mediated and do not require gene transcription and translation. One of these non-genomic effects is the inhibition of adrenergic agonist transport into airway vascular smooth muscle cells with an increase of adrenergic agonist concentrations at adrenergic receptor sites and enhance the physiological effects of endogenous adrenergic agonists (e. g. locally released norepinephrine from noradrenergic neurons) or exogenous adrenergic agonists (e. g. inhaled beta-adrenergic agonists).

Evaluation of the Efficacy and Safety of a Fixed-dose, Single-capsule Budesonide-formoterol Combination in Uncontrolled Asthma [Completed]
To evaluate the efficacy and safety of a fixed-dose, single-capsule budesonide(400g)-formoterol(12g) combination, in comparison with budesonide alone, both delivered via a dry powder inhaler, in 181 patients with uncontrolled asthma. This was Randomized, double-blind, multicenter, phase III, parallel clinical trial.

Assess the Efficacy and Safety of Rhinocort Aqua [Completed]
The purpose of this study is to compare Rhinocort with placebo in pediatric subjects aged 2-5 years with allergic rhinitis to study effects on nasal symptoms such as sneezing, runny and stuffy noses.

Trial on the Effect of Budesonide/Formoterol and Inhaled Budesonide Alone on Exercise-Induced Asthma [Terminated]
The purpose of this study is to find out if Symbicort (budesonide/formoterol), a new combination asthma medication, is more effective than budesonide alone in controlling exercise induced asthma. The investigators hypothesize that in children and adults who suffer from asthma and exercise induced asthma there will be less decline in lung function associated with exercise when they receive the study medication.

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Reports of Suspected Entocort EC (Budesonide) Side Effects

OFF Label USE (33)Diarrhoea (30)Drug Dose Omission (24)Crohn's Disease (23)Malaise (22)Dizziness (11)Nausea (11)Gastrointestinal Haemorrhage (10)Drug Ineffective (10)Intentional Drug Misuse (9)more >>

Page last updated: 2015-08-10

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