Gentamicin (Gentamicin Sulfate Ophthalmic) - Side Effects and Adverse Reactions

ADVERSE REACTIONS

Bacterial and fungal corneal ulcers have developed during treatment with gentamicin ophthalmic preparations.

The most frequently reported adverse reactions are ocular burning and irritation upon drug instillation, non-specific conjunctivitis, conjunctival epithelial defects and conjunctival hyperemia.

Other adverse reactions which have occurred rarely are allergic reactions, thrombocytopenic purpura and hallucinations.

REPORTS OF SUSPECTED GENTAMICIN SIDE EFFECTS / ADVERSE REACTIONS

Possible Gentamicin side effects / adverse reactions in 57 year old female

Reported by a health professional (non-physician/pharmacist) from Denmark on 2011-10-03

Patient: 57 year old female

Reactions: Neutropenic Sepsis, Toxic Epidermal Necrolysis

Adverse event resulted in: death

Suspect drug(s):
Piperacillin and Tazobactam
    Dosage: 4.5 g;qid;iv
    Indication: Neutropenic Infection
    Start date: 2011-08-10

Gentamicin
    Indication: Neutropenic Infection
    Start date: 2011-08-10

Gemcitabine Hydrochloride
    Dosage: 1596 mg; iv
    Indication: Pancreatic Carcinoma
    Start date: 2011-07-29
    End date: 2011-07-29

Other drugs received by patient: Bisoprolol; Diazepam; Ursodexoycholic Acid; Zopiclone; Oxycontin; Warfarin Sodium; Irbesartan; Furosemide; Isosorbide Mononitrate; Pantoprazole; Simvastatin; Dothiepin Hydrochloride

Possible Gentamicin side effects / adverse reactions in 51 year old female

Reported by a health professional (non-physician/pharmacist) from Singapore on 2011-10-05

Patient: 51 year old female

Reactions: Rash, Dermatitis Exfoliative

Suspect drug(s):
Phenytoin
    Dosage: unk
    Start date: 2011-08-04
    End date: 2011-08-20

Ciprofloxacin HCL
    Dosage: unk
    Start date: 2011-08-16
    End date: 2011-08-18

Gentamicin
    Dosage: unk
    Start date: 2011-08-18
    End date: 2011-08-20

Possible Gentamicin side effects / adverse reactions in 57 year old female

Reported by a health professional (non-physician/pharmacist) from United Kingdom on 2011-10-05

Patient: 57 year old female weighing 57.0 kg (125.4 pounds)

Reactions: Neutropenic Sepsis, Toxic Epidermal Necrolysis

Adverse event resulted in: death, hospitalization

Suspect drug(s):
Gemcitabine
    Dosage: 1596.00-mg/intravenous (not otherwise specified)
    Indication: Pancreatic Carcinoma
    Start date: 2011-07-29
    End date: 2011-07-29

Tazocin (Tazocin)
    Dosage: 4.50-g-4.00 times per-1.0days/intravenous (not otherwise specified)
    Indication: Neutropenic Infection
    Start date: 2011-08-10

Gentamicin
    Indication: Neutropenic Infection
    Start date: 2011-08-10

Other drugs received by patient: Bisoprolol Fumarate; Simvastatin; Ursodiol; Warfarin Sodium; Zopiclone (Zopiclone); Diazepam; Isosorbid Mononitrate (Isosorbide Mononitrate); Irbesartan (Irbesartan); Dothiepin Hydrochloride; Furosemide; Oxycontin; Pantoprazole