Clinical studies comparing Humalog Mix75/25 with human insulin mixtures did not demonstrate a difference in frequency of adverse events between the two treatments.
Adverse events commonly associated with human insulin therapy include the following:
Body as a Whole --allergic reactions (see PRECAUTIONS)
Skin and Appendages --injection site reaction, lipodystrophy, pruritus, rash
Other --hypoglycemia (see WARNINGS and PRECAUTIONS)