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Kemstro (Baclofen) - Drug Interactions, Contraindications, Overdosage, etc

 
 



DRUG INTERACTIONS

Drug interactions

The central nervous system depressant effects of baclofen may be additive to those of alcohol and other CNS depressants.

Contraindications

KEMSTRO™ is contraindicated in patients who are hypersensitive to any component of this product.

Drug Abuse and Dependence

Overdosage

Signs and Symptoms

Vomiting, muscular hypotonia, drowsiness, accommodation disorders, coma, respiratory depression, and seizures.

Treatment

In the alert patient, empty the stomach promptly by induced emesis followed by lavage. In the obtunded patient, secure the airway with a cuffed endotracheal tube before beginning lavage (do not induce emesis). Maintain adequate respiratory exchange, do not use respiratory stimulants. It is unknown what effect hemodialysis or peritoneal dialysis has on the serum concentration of baclofen.

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