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Kenalog-40 (Triamcinolone Acetonide) - Side Effects and Adverse Reactions



(listed alphabetically under each subsection)

The following adverse reactions may be associated with corticosteroid therapy:

Allergic reactions: Anaphylactoid reaction, anaphylaxis, angioedema.

Cardiovascular: Bradycardia, cardiac arrest, cardiac arrhythmias, cardiac enlargement, circulatory collapse, congestive heart failure, fat embolism, hypertension, hypertrophic cardiomyopathy in premature infants, myocardial rupture following recent myocardial infarction (see WARNINGS), pulmonary edema, syncope, tachycardia, thromboembolism, thrombophlebitis, vasculitis.

Dermatologic: Acne, allergic dermatitis, cutaneous and subcutaneous atrophy, dry scaly skin, ecchymoses and petechiae, edema, erythema, hyperpigmentation, hypopigmentation, impaired wound healing, increased sweating, lupus erythematosus-like lesions, purpura, rash, sterile abscess, striae, suppressed reactions to skin tests, thin fragile skin, thinning scalp hair, urticaria.

Endocrine: Decreased carbohydrate and glucose tolerance, development of cushingoid state, glycosuria, hirsutism, hypertrichosis, increased requirements for insulin or oral hypoglycemic agents in diabetes, manifestations of latent diabetes mellitus, menstrual irregularities, secondary adrenocortical and pituitary unresponsiveness (particularly in times of stress, as in trauma, surgery, or illness), suppression of growth in pediatric patients.

Fluid and electrolyte disturbances: Congestive heart failure in susceptible patients, fluid retention, hypokalemic alkalosis, potassium loss, sodium retention.

Gastrointestinal: Abdominal distention, bowel/bladder dysfunction (after intrathecal administration), elevation in serum liver enzyme levels (usually reversible upon discontinuation), hepatomegaly, increased appetite, nausea, pancreatitis, peptic ulcer with possible perforation and hemorrhage, perforation of the small and large intestine (particularly in patients with inflammatory bowel disease), ulcerative esophagitis.

Metabolic: Negative nitrogen balance due to protein catabolism.

Musculoskeletal: Aseptic necrosis of femoral and humeral heads, calcinosis (following intra-articular or intralesional use), Charcot-like arthropathy, loss of muscle mass, muscle weakness, osteoporosis, pathologic fracture of long bones, post injection flare (following intra-articular use), steroid myopathy, tendon rupture, vertebral compression fractures.

Neurologic/Psychiatric: Convulsions, depression, emotional instability, euphoria, headache, increased intracranial pressure with papilledema (pseudotumor cerebri) usually following discontinuation of treatment, insomnia, mood swings, neuritis, neuropathy, paresthesia, personality changes, psychic disorders, vertigo. Arachnoiditis, meningitis, paraparesis/paraplegia, and sensory disturbances have occurred after intrathecal administration (see WARNINGS: Neurologic).

Ophthalmic: Exophthalmos, glaucoma, increased intraocular pressure, posterior subcapsular cataracts, rare instances of blindness associated with periocular injections.

Other: Abnormal fat deposits, decreased resistance to infection, hiccups, increased or decreased motility and number of spermatozoa, malaise, moon face, weight gain.


Below is a sample of reports where side effects / adverse reactions may be related to Kenalog-40. The information is not vetted and should not be considered as verified clinical evidence.

Possible Kenalog-40 side effects / adverse reactions in 65 year old male

Reported by a consumer/non-health professional from United States on 2011-10-04

Patient: 65 year old male weighing 70.0 kg (154.0 pounds)

Reactions: Vomiting, Pneumonia, Dystonia, Sensation of Heaviness, Ataxia, Fall, Speech Disorder, Oedema Peripheral, Vision Blurred, Dizziness, Hallucination, Hypertension

Adverse event resulted in: life threatening event, hospitalization, disablity

Suspect drug(s):

Other drugs received by patient: Lidocaine

Possible Kenalog-40 side effects / adverse reactions in 51 year old female

Reported by a health professional (non-physician/pharmacist) from United States on 2011-10-12

Patient: 51 year old female

Reactions: Agitation, Paranoia, Suicide Attempt, Suicidal Ideation

Adverse event resulted in: hospitalization

Suspect drug(s):

Other drugs received by patient: Levothyroxine Sodium; Sertraline Hydrochloride; Topiramate

Possible Kenalog-40 side effects / adverse reactions in 41 year old female

Reported by a consumer/non-health professional from United States on 2011-11-01

Patient: 41 year old female weighing 45.0 kg (99.0 pounds)

Reactions: Night Sweats, Increased Appetite, Injection Site Reaction, Insomnia, Mood Swings, Muscle Spasms

Suspect drug(s):
    Dosage: routr: bursa injection.28apr11
    Indication: Bursitis
    Start date: 2011-04-08

    Start date: 2011-04-08

Other drugs received by patient: Cymbalta; Estrogen Patch

See index of all Kenalog-40 side effect reports >>

Drug label data at the top of this Page last updated: 2010-09-29

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